This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ STEAP1 / STEAP Antibody (C-Terminus) LS-B2828
catalog :
LS-B2828
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
90085
AntibodyName :
LS-B2828
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ STEAP1 / STEAP Antibody (C-Terminus) LS-B2828
Specificity :
Recognizes STEAP1 (six transmembrane epithelial antigen of the prostate), a 39kD protein which is a member of a family of cell surface serpentine transmembrane antigens of the prostate. STEAP1 is predominantly expressed in human prostate and is up-regulated in several cancer lines including prostate, ovarian, cervical, breast, testicular, bladder, colon and Ewing sarcoma. It is significantly expressed at cell-cell junctions and has been shown to be a target of human CD8 T cells. This indicates that it could be used as a potential target for cancer immunotherapy. Does not cross-react with other STEAP-proteins.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
PBS, 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
An 18 amino acid peptide located near the C-Terminus of human STEAP1
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
STEAP1 / STEAP
StandardGeneSymbol :
STEAP1
Reactivity :
Human
Usage :
IHC, IHC-P (5 µg/ml), WB (1 - 2 µg/ml)
ShortWebDescription :
STEAP antibody LS-B2828 is an unconjugated rabbit polyclonal antibody to human STEAP (STEAP1) (C-Terminus). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
UsageText :
Immunohistochemistry: LS-B2828 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2828 was determined to be 5 ug/ml. Western Blot: LS-B2828 detects a band of approximately 40kD in human spleen cell lysates.
Synonyms :
STEAP1, Metalloreductase STEAP1, PRSS24, STEAP
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.