IHC-plus™ CD95 / FAS Antibody (clone LT95) LS-B2820 | LifeSpan Biosciences LS-B2820 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

IHC-plus™ CD95 / FAS Antibody (clone LT95) LS-B2820

catalog :

LS-B2820

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

LT95

reactivity :

human

application :

immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

LifeSpan Biosciences product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Blok E, van den Bulk J, Dekker Ensink N, Derr R, Kanters C, Bastiaannet E, et al. Combined evaluation of the FAS cell surface death receptor and CD8+ tumor infiltrating lymphocytes as a prognostic biomarker in breast cancer. Oncotarget. 2017;8:15610-15620 pubmed publisher

image

image 1 :

Anti-FAS antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

product information

AntibodyID :

90077

AntibodyName :

LS-B2820

TargetSpecies :

Human

Host Species :

Mouse

Product Name :

IHC-plus™ CD95 / FAS Antibody (clone LT95) LS-B2820

Specificity :

The antibody LT95 reacts with CD95 (Fas/APO-1), a 46 kDa single chain type I glycoprotein of the tumor necrosis factor/nerve growth factor (TNF/NGF) receptor superfamily, expressed on a variety of normal and neoplastic cells.It seems that the antibody LT95 does not induce Fas mediated apoptosis, although it cross-blocks anti-Fas DX2 antibody that recognizes a functional epitope of Fas molecule.

ClonalityDesc :

Monoclonal

CloneName :

LT95

AntibodyModification :

Unconjugated

PresentationDesc :

PBS, pH 7.4, 15 mM Sodium Azide

ImmunogenType :

Cells

ImmunogenDesc :

HUT-78 human T cell lymphoma cell line

PurificationDesc :

Purified by protein-A affinity chromatography. Greater than 95% by SDS-PAGE.

RecommendedStorageDesc :

Store at 2°C to 8°C. Do not freeze.

IsotypeName :

IgG1

Gene :

CD95 / FAS

StandardGeneSymbol :

FAS

gene family :

TNF Receptor

Reactivity :

Human

Usage :

Flo, IHC, IHC-P (10 µg/ml)

ShortWebDescription :

FAS antibody LS-B2820 is an unconjugated mouse monoclonal antibody to human FAS (CD95). Validated for Flow and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.

Synonyms :

FAS, ALPS1A, APO-1, APT1, Apo-1 antigen, APO-1 cell surface antigen, Apo11 antigen, Apoptosis antigen 1, CD95 antigen, Delta Fas/APO-1/CD95, Fas AMA, FAS1, Fasl receptors, FASLG receptor, FASTM, FAS 827dupA, Fasl receptor, TNFRSF6, CD95

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.