PathPlus™ GZMB / Granzyme B Antibody (N-Terminus) LS-B2783 | LifeSpan Biosciences LS-B2783 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

PathPlus™ GZMB / Granzyme B Antibody (N-Terminus) LS-B2783

catalog :

LS-B2783

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

immunohistochemistry - paraffin section

more info or order :

LifeSpan Biosciences product webpage

citations: 1

Reference
Limagne E, Thibaudin M, Nuttin L, Spill A, Derangère V, Fumet J, et al. Trifluridine/Tipiracil plus Oxaliplatin Improves PD-1 Blockade in Colorectal Cancer by Inducing Immunogenic Cell Death and Depleting Macrophages. Cancer Immunol Res. 2019;7:1958-1969 pubmed publisher

image

image 1 :

Anti-GZMB / Granzyme B antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

product information

AntibodyID :

90038

AntibodyName :

LS-B2783

TargetSpecies :

Human

Host Species :

Rabbit

Product Name :

PathPlus™ GZMB / Granzyme B Antibody (N-Terminus) LS-B2783

ClonalityDesc :

Polyclonal

AntibodyModification :

Unconjugated

AntigenModification :

N-Terminus

PresentationDesc :

10 mM PBS, pH 7.4, 0.1% Sodium Azide, 1% BSA

ImmunogenType :

Synthetic peptide

ImmunogenDesc :

A synthetic peptide from N-Terminus of human Granzyme B

PurificationDesc :

Immunoaffinity purified

RecommendedStorageDesc :

Aliquot and freeze at -20°C. Avoid freeze-thaw cycles.

Gene :

GZMB / Granzyme B

StandardGeneSymbol :

GZMB

gene family :

Protease

Subfamily :

Serine S1

Reactivity :

Mouse, Rat, Human

Usage :

IHC-P (15 µg/ml)

ShortWebDescription :

Granzyme B antibody LS-B2783 is an unconjugated rabbit polyclonal antibody to Granzyme B (GZMB) (N-Terminus) from human. It is reactive with human, mouse and rat. Validated for IHC. Cited in 1 publication.

UsageText :

Immunohistochemistry: LS-B2783 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working dilution for LS-B2783 was determined to be 1:100.

Synonyms :

GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.