product summary
Loading...
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ ACVR1B / ALK4 Antibody LS-B2695
catalog :
LS-B2695
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Miller D, Bloxham R, Jiang M, Gori I, Saunders R, Das D, et al. The Dynamics of TGF-β Signaling Are Dictated by Receptor Trafficking via the ESCRT Machinery. Cell Rep. 2018;25:1841-1855.e5 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B2695 image 1
Western blot of ACVR1B in human kidney tissue lysate with ACVR1B antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
image 2 :
LifeSpan Biosciences LS-B2695 image 2
Anti-ACVR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
product information
AntibodyID :
88491
AntibodyName :
LS-B2695
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ ACVR1B / ALK4 Antibody LS-B2695
Specificity :
At least three isoforms of ACVR1B are known to exist. This antibody is predicted to have no cross-reactivity to ACVR1 or ACVR1C.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS containing 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A 14 AA synthetic peptide near the C-Terminus of human ACVR1B. The immunogen is located within aa 140-190 of ACVR1B.
PurificationDesc :
Peptide Column Affinity Chromatography
RecommendedStorageDesc :
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
ACVR1B / ALK4
BlockingPeptide :
LS-E30568
StandardGeneSymbol :
ACVR1B
gene family :
Protein Kinase
Subfamily :
Activin/TGFb
Reactivity :
Mouse, Human
Usage :
ELISA, IHC, IHC-P (5 µg/ml), WB (1 µg/ml)
ShortWebDescription :
ALK4 antibody LS-B2695 is an unconjugated rabbit polyclonal antibody to ALK4 (ACVR1B) from human. It is reactive with human and mouse. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
ACVR1B antibody can be used for detection of ACVR1B by Western blot at 1 ug/mL. Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Western Blot:
Synonyms :
ACVR1B, ACTR-IB, ACTRIB, ALK4, Activin receptor type IB, Activin A Receptor Type IB, Activin A receptor, type IB, Activin receptor-like kinase 4, ACVRLK4, ALK-4, Activin receptor type-1B, SKR2-2, SKR2
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.