product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ MANF / ARMET Antibody LS-B2688
catalog :
LS-B2688
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 3
Reference
Danilova T, Galli E, Pakarinen E, Palm E, Lindholm P, Saarma M, et al. Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Is Highly Expressed in Mouse Tissues With Metabolic Function. Front Endocrinol (Lausanne). 2019;10:765 pubmed publisher
Galli E, Rossi J, Neumann T, Andressoo J, Drinda S, Lindholm P. Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Upregulated with Therapeutic Fasting in Humans and Diet Fat Withdrawal in Obese Mice. Sci Rep. 2019;9:14318 pubmed publisher
Guo J, Cui Y, Liu Q, Yang Y, Li Y, Weng L, et al. Piperine ameliorates SCA17 neuropathology by reducing ER stress. Mol Neurodegener. 2018;13:4 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B2688 image 1
Western blot of MANF in mouse brain tissue lysate with MANF antibody at (A) 1 and (B) 2 ug/ml. Below: Immunohistochemistry of MANF in human brain tissue with MANF antibody at 2.5 ug/ml.
image 2 :
LifeSpan Biosciences LS-B2688 image 2
Anti-MANF / ARMET antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
image 3 :
LifeSpan Biosciences LS-B2688 image 3
Immunofluorescence of MANF in Human Brain cells with MANF antibody at 20 ug/ml.
product information
AntibodyID :
88484
AntibodyName :
LS-B2688
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ MANF / ARMET Antibody LS-B2688
Specificity :
This antibody does not cross-react with CDNF.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS containing 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A 12 AA synthetic peptide near the C-Terminus of human MANF. The immunogen is located within the last 50 AA of MANF.
PurificationDesc :
Peptide Column Affinity Chromatography
RecommendedStorageDesc :
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
MANF / ARMET
BlockingPeptide :
LS-E30396
StandardGeneSymbol :
MANF
Reactivity :
Mouse, Rat, Human
Usage :
ELISA, IF, IHC, IHC-P (5 µg/ml), WB (1 - 2 µg/ml)
ShortWebDescription :
ARMET antibody LS-B2688 is an unconjugated rabbit polyclonal antibody to ARMET (MANF) from human. It is reactive with human, mouse and rat. Validated for ELISA, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
UsageText :
MANF antibody can be used for detection of MANF by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL. Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Western Blot: 20 kDa
Synonyms :
MANF, ARP, ARMET, Arginine-rich protein, Protein ARMET
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.