product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ LRP1 / CD91 Antibody (clone 5A6) LS-B2675
catalog :
LS-B2675
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5A6
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Au Yeung C, Yeung T, Achreja A, Zhao H, Yip K, Kwan S, et al. ITLN1 modulates invasive potential and metabolic reprogramming of ovarian cancer cells in omental microenvironment. Nat Commun. 2020;11:3546 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B2675 image 1
Anti-LRP1 / Low Density LRP antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
product information
AntibodyID :
88468
AntibodyName :
LS-B2675
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ LRP1 / CD91 Antibody (clone 5A6) LS-B2675
Specificity :
Recognises the 85kDa cleaved fragment of Low Density LRP (extracellular domain).
ClonalityDesc :
Monoclonal
CloneName :
5A6
AntibodyModification :
Unconjugated
PresentationDesc :
0.05 M Sodium Phosphate, pH 6.6, 0.1 M NaCl, 1 mM EDTA
ImmunogenType :
Native protein
ImmunogenDesc :
Full length native protein (purified) (Human).
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at -70°C.
IsotypeName :
IgG2b
Gene :
LRP1 / CD91
StandardGeneSymbol :
LRP1
Reactivity :
Rabbit, Mouse, Human
Usage :
Flo, IHC, IHC-P (10 µg/ml), WB
ShortWebDescription :
CD91 antibody LS-B2675 is an unconjugated mouse monoclonal antibody to CD91 (LRP1) from human. It is reactive with human, mouse and rabbit. Validated for Flow, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
Immunohistochemistry: LS-B2675 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2675 was determined to be 10 ug/ml. Western blot requires non-reducing conditions.
Synonyms :
LRP1, Apolipoprotein E receptor, CD91 antigen, CD91, A2MR, IGFBP3R, Alpha-2-macroglobulin receptor, TGFBR5, Type V tgf-beta receptor, APOER, APR, LRP, LRP-1, LRP-85, LRP-515, LRPICD
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.