product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ SDF1 / CXCL12 Antibody LS-B2437
catalog :
LS-B2437
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:50; loading ...; fig 3b
Wang C, Ying J, Nie X, Zhou T, Xiao D, Swarnkar G, et al. Targeting angiogenesis for fracture nonunion treatment in inflammatory disease. Bone Res. 2021;9:29 pubmed publisher
Kumar V, Mansfield J, Fan R, MACLEAN A, Li J, Mohan M. miR-130a and miR-212 Disrupt the Intestinal Epithelial Barrier through Modulation of PPARγ and Occludin Expression in Chronic Simian Immunodeficiency Virus-Infected Rhesus Macaques. J Immunol. 2018;200:2677-2689 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B2437 image 1
Anti-CXCL12 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
product information
AntibodyID :
83780
AntibodyName :
LS-B2437
TargetSpecies :
Rat
Host Species :
Rabbit
Product Name :
IHC-plus™ SDF1 / CXCL12 Antibody LS-B2437
Specificity :
Recognizes rat SDF-1b. Species cross-reactivity: mouse.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
0.05% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
E. coli-expressed mouse SDF-1b.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
SDF1 / CXCL12
StandardGeneSymbol :
CXCL12
gene family :
Intercrine
Subfamily :
Intercrine alpha
Reactivity :
Mouse, Rat, Human
Usage :
IHC, IHC-P (5 µg/ml), IP (1:300 - 1:500), WB (1:1000)
ShortWebDescription :
CXCL12 antibody LS-B2437 is an unconjugated rabbit polyclonal antibody to CXCL12 (SDF1) from rat. It is reactive with human, mouse and rat. Validated for IHC, IP and WB.
UsageText :
Immunohistochemistry: LS-B2437 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2437 was determined to be 5 ug/ml.
Synonyms :
CXCL12, C-X-C motif chemokine 12, HIRH, IRH, SDF-1, SDF-1b, SDF1A, SDF1B, TPAR1, TLSF-a, TLSF-b, SDF-1a, SDF1, Sdf1alpha, Stromal cell-derived factor 1, TLSF, HSDF-1, PBSF, SCYB12
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.