This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ PLN / Phospholamban Antibody (aa2-25) LS-B2358
catalog :
LS-B2358
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
product information
AntibodyID :
83546
AntibodyName :
LS-B2358
TargetSpecies :
Dog
Host Species :
Mouse
Product Name :
IHC-plus™ PLN / Phospholamban Antibody (aa2-25) LS-B2358
Specificity :
Recognizes canine PLB. Recognizes an epitope between aa 9-17 of canine PLB. Detects bands of ~25kD (non-reducing conditions; representing the pentameric form of PLB) and ~5kD (reducing conditions; representing the monomeric form of PLB) by Western Blot. Species cross-reactivity: human, mouse, rat, rabbit chicken, sheep, porcine and guinea pig.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa2-25
PresentationDesc :
PBS, 0.05% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to aa 2-25 (D2KVQYLTRSAIRRASTIEMPQQAR25) of dog PLB (phospholamban). Percent identity by BLAST analysis: Bovine, Dog, Pig (100%); Human, Monkey, Marmoset, Mouse, Rat, Panda, Bat, Horse, Rabbit, Opossum (96%); Gorilla, Gibbon (92%); Elephant (88%).
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG2a
Gene :
PLN / Phospholamban
StandardGeneSymbol :
PLN
Reactivity :
Dog, Bovine, Pig, Human
Usage :
ICC, IHC, IHC-P (5 µg/ml), IP, WB
ShortWebDescription :
Phospholamban antibody LS-B2358 is an unconjugated mouse monoclonal antibody to Phospholamban (PLN) (aa2-25) from dog. It is reactive with human, bovine, dog and other species. Validated for ICC, IHC, IP and WB.
UsageText :
Immunohistochemistry: LS-B2358 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2358 was determined to be 5 ug/ml. Western Blot: 2 ug/ml Detects bands of ~25kD (non-reducing conditions; representing the pentameric form of PLB) and ~5kD (reducing conditions; representing the monomeric form of PLB). Function: Increases the calcium uptake in ventricular SR vesicles.
Synonyms :
PLN, CMD1P, CMH18, PLB, Cardiac phospholamban, Phospholamban
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.