product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ MBP / Myelin Basic Protein Antibody (aa130-136) LS-B2231
catalog :
LS-B2231
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 1
Reference
. Cranial nerve involvement in patients with MOG antibody-associated disease. Neurol Neuroimmunol Neuroinflamm. 2019;6:e543 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B2231 image 1
Anti-Myelin Basic Protein antibody IHC of human brain, oligodendrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
product information
AntibodyID :
63913
AntibodyName :
LS-B2231
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ MBP / Myelin Basic Protein Antibody (aa130-136) LS-B2231
Specificity :
Recognizes residues 130-136 in human myelin basic protein (21.5kD and 18.5kD molecular forms).
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa130-136
PresentationDesc :
PBS, pH 7.4, no preservatives.
ImmunogenType :
Purified protein
ImmunogenDesc :
Purified human myelin basic protein.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG2b
Gene :
MBP / Myelin Basic Protein
StandardGeneSymbol :
MBP
Reactivity :
Rabbit, Mouse, Goat, Sheep, Rat, Primate, Human
Usage :
ELISA (10 - 20 µg/ml), IHC, IHC-Fr, IHC-P (5 µg/ml), WB (1 - 2 µg/ml)
ShortWebDescription :
Myelin Basic Protein antibody LS-B2231 is an unconjugated mouse monoclonal antibody to Myelin Basic Protein (MBP) (aa130-136) from human. It is reactive with human, mouse, rat and other species. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
Immunohistochemistry: LS-B2231 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2231 was determined to be 5 ug/ml.
Synonyms :
MBP, Myelin A1 protein, Myelin basic protein
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.