This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PathPlus™ DNMT / DNMT1 Antibody (aa637-650, clone 60B1220.1) LS-B2128
catalog :
LS-B2128
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
60B1220.1

The same clone is also sold as:
reactivity :
human
application :
western blot, immunoprecipitation, immunohistochemistry - paraffin section
product information
AntibodyID :
62381
AntibodyName :
LS-B2128
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PathPlus™ DNMT / DNMT1 Antibody (aa637-650, clone 60B1220.1) LS-B2128
Specificity :
A synthetic peptide corresponding to amino acids 637-650 (EKDDREDKENAFKR) of human Dnmt1 (Genbank Accession No. NP_001370). It will cross react with mouse Dnmt1.
ClonalityDesc :
Monoclonal
CloneName :
60B1220.1
AntibodyModification :
Unconjugated
AntigenModification :
aa637-650
PresentationDesc :
PBS, 0.05% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A synthetic peptide corresponding to amino acids 637-650 (EKDDREDKENAFKR) of human Dnmt1 (Genbank Accession No. NP_001370). It will cross react with mouse Dnmt1. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Panda, Bat, Horse, Rabbit (100%); Sheep, Hamster, Elephant, Dog, Bovine, Pig (93%).
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
DNMT / DNMT1
StandardGeneSymbol :
DNMT1
gene family :
C5-methyltransferase
Reactivity :
Rabbit, Mouse, Horse, Bat, Human, Monkey
Usage :
ChrIP, IHC-P (5 - 10 µg/ml), IP, WB (2 - 4 µg/ml)
ShortWebDescription :
DNMT1 antibody LS-B2128 is an unconjugated mouse monoclonal antibody to DNMT1 (DNMT) (aa637-650) from human. It is reactive with human, mouse, bat and other species. Validated for ChrIP, IHC, IP and WB.
UsageText :
Immunohistochemistry: LS-B2128 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2128 was determined to be 5 ug/ml.
Synonyms :
DNMT1, AIM, CXXC finger protein 9, CXXC9, DNA methyltransferase 1, DNMT, DNA methyltransferase HsaI, DNA MTase HsaI, HSN1E, M.HsaI, MCMT
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.