product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PathPlus™ TLR4 Antibody (aa100-200, clone 76B357.1) LS-B2070
catalog :
LS-B2070
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
76B357.1
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Nihon Yanagi Y, Terai K, Murano T, Matsumoto T, Okazumi S. Tissue expression of Toll-like receptors 2 and 4 in sporadic human colorectal cancer. Cancer Immunol Immunother. 2012;61:71-7 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B2070 image 1
Anti-TLR4 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
product information
AntibodyID :
53020
AntibodyName :
LS-B2070
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PathPlus™ TLR4 Antibody (aa100-200, clone 76B357.1) LS-B2070
Specificity :
The amino acid sequence used has 100% identity in human, chimp, baboon, Chinese hamster, and rat; 93% identity in bovine and pig; 85% identity in sheep and 78% identity in cat, horse and mouse.
ClonalityDesc :
Monoclonal
CloneName :
76B357.1
AntibodyModification :
Unconjugated
AntigenModification :
aa100-200
PresentationDesc :
PBS, 0.05% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide from human TLR4.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG2b,k
Gene :
TLR4
StandardGeneSymbol :
TLR4
gene family :
Toll-like Receptor
Reactivity :
Mouse, Rat, Human
Usage :
Flo, IHC, IHC-P (5 µg/ml), WB (1 - 3 µg/ml)
ShortWebDescription :
TLR4 antibody LS-B2070 is an unconjugated mouse monoclonal antibody to TLR4 (aa100-200) from human. It is reactive with human, mouse and rat. Validated for Flow, IHC and WB. Cited in 1 publication.
UsageText :
Immunohistochemistry: LS-B2070 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2070 was determined to be 5 ug/ml.
Synonyms :
TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.