This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ BIRC7 / Livin Antibody (clone 88C570) LS-B2018
catalog :
LS-B2018
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
88C570

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
52188
AntibodyName :
LS-B2018
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ BIRC7 / Livin Antibody (clone 88C570) LS-B2018
Specificity :
The Livin antibody, clone 88C570 has been shown to recognize both Livin alpha (~39 kD) and Livin beta (~37 kD) isoforms (Nachmias et al, 2003). 2. also recognizes the 30 kD (p30-Livin alpha) and 28 kD (p28-Livin beta) apoptotic cleavage fragments of Livin alpha and beta, respectively (Nachmias et al, 2003). Apoptotic cleavage fragments of Livin have also been referred to as truncated livin (tLivin) (Nachmias et al, 2007). 3. The specificity has been validated using Livin shRNA (Quiping et al, 2004).
ClonalityDesc :
Monoclonal
CloneName :
88C570
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.05% Sodium Azide, 0.05% BSA
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human livin protein.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
BIRC7 / Livin
StandardGeneSymbol :
BIRC7
gene family :
Apoptosis
Reactivity :
Human
Usage :
IHC, IHC-P (10 µg/ml), WB (1 - 2 µg/ml)
ShortWebDescription :
Livin antibody LS-B2018 is an unconjugated mouse monoclonal antibody to human Livin (BIRC7). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
UsageText :
Immunohistochemistry: LS-B2018 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2018 was determined to be 10 ug/ml.
Synonyms :
BIRC7, KIAP, Livin inhibitor of apoptosis, MLIAP, ML-IAP, RNF50, RING finger protein 50, LIVIN
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.