product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ CXCR4 Antibody (clone 12G5) LS-B1986
catalog :
LS-B1986
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
12G5
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Reference
Isnardi I, Ng Y, Menard L, Meyers G, Saadoun D, Srdanovic I, et al. Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Blood. 2010;115:5026-36 pubmed publisher
Thompson B, Jin Y, Wu K, Colvin R, Luster A, Birnbaumer L, et al. Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling. J Biol Chem. 2007;282:9547-55 pubmed
image
image 1 :
LifeSpan Biosciences LS-B1986 image 1
Anti-CXCR4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
image 2 :
LifeSpan Biosciences LS-B1986 image 2
Human peripheral blood lymphocytes stained with purified 12G5, followed by biotinylated anti-mouse IgG and Sav-PE
product information
AntibodyID :
52156
AntibodyName :
LS-B1986
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ CXCR4 Antibody (clone 12G5) LS-B1986
ClonalityDesc :
Monoclonal
CloneName :
12G5
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.2, 0.09% Sodium Azide
ImmunogenDesc :
CP-MAC-infected Sup-T1 cells
PurificationDesc :
Purified from tissue culture supernatant by affinity chromatography.
RecommendedStorageDesc :
Store undiluted at 4°C. Avoid freezing.
IsotypeName :
IgG2a,k
Gene :
CXCR4
StandardGeneSymbol :
CXCR4
gene family :
GPCR
Subfamily :
Chemokine
Reactivity :
Human, Baboon, Chimpanzee, African green monkey, Cynomolgus monkey, Rhesus monkey, Sooty Mangabey
Usage :
Flo, IF, IHC, IHC-Fr, IHC-P (10 µg/ml)
ShortWebDescription :
CXCR4 antibody LS-B1986 is an unconjugated mouse monoclonal antibody to CXCR4 from human. It is reactive with human, african green monkey, baboon and other species. Validated for Flow, IF and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
UsageText :
Immunohistochemistry: LS-B1986 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1986 was determined to be 10 ug/ml.
Synonyms :
CXCR4, CD184, CD184 antigen, Cmkar4, Cxc chemokine receptor 4, CXCR-4, CXC-R4, D2S201E, FB22, Fusin, HM89, LCR1, NPY3R, NPYRL, NPYY3R, Npyy3, HSY3RR, SDF-1 receptor, WHIM, C-x-c chemokine receptor 4, LESTR, Neuropeptide Y receptor Y3, NPYR
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.