product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PathPlus™ CD40 Antibody (clone HB14) LS-B1956
catalog :
LS-B1956
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HB14
reactivity :
human
application :
immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Reference
Iwata Y, Matsushita T, Horikawa M, DiLillo D, Yanaba K, Venturi G, et al. Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. Blood. 2011;117:530-41 pubmed publisher
Jayakumar A, Donovan M, Tripathi V, Ramalho Ortigao M, McDowell M. Leishmania major infection activates NF-kappaB and interferon regulatory factors 1 and 8 in human dendritic cells. Infect Immun. 2008;76:2138-48 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B1956 image 1
Anti-CD40 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
image 2 :
LifeSpan Biosciences LS-B1956 image 2
Human peripheral blood lymphocytes stained with purified HB14, followed by anti-mouse IgGs FITC
product information
AntibodyID :
51245
AntibodyName :
LS-B1956
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PathPlus™ CD40 Antibody (clone HB14) LS-B1956
Specificity :
Recognizes human CD40.
ClonalityDesc :
Monoclonal
CloneName :
HB14
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.2, 0.09% Sodium Azide
ImmunogenType :
Cells
ImmunogenDesc :
Human B cell line.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C. Store undiluted.
IsotypeName :
IgG1,k
Gene :
CD40
StandardGeneSymbol :
CD40
gene family :
TNF Receptor
Reactivity :
Human, Monkey
Usage :
Flo (0.5 µg/10E6 cells), IHC, IHC-P (10 µg/ml)
ShortWebDescription :
CD40 antibody LS-B1956 is an unconjugated mouse monoclonal antibody to CD40 from human. It is reactive with human and monkey. Validated for Flow and IHC. Cited in 2 publications.
UsageText :
Immunohistochemistry: LS-B1956 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1956 was determined to be 10 ug/ml.
Synonyms :
CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.