product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PathPlus™ FOXC1 Antibody (aa250-300) LS-B1800
catalog :
LS-B1800
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 1
Reference
Xu Y, Yao R, Li J, Zhou Y, Mao F, Pan B, et al. FOXC1 overexpression is a marker of poor response to anthracycline-based adjuvant chemotherapy in sporadic triple-negative breast cancer. Cancer Chemother Pharmacol. 2017;79:1205-1213 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B1800 image 1
Anti-FOXC1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
product information
AntibodyID :
48209
AntibodyName :
LS-B1800
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
PathPlus™ FOXC1 Antibody (aa250-300) LS-B1800
Specificity :
A portion of amino acids 250-300 of human FOXC1.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa250-300
PresentationDesc :
PBS, 0.05% Sodium Azide, 0.2% Gelatin
ImmunogenType :
Protein fragment
ImmunogenDesc :
A portion of amino acids 250-300of human FOXC1.
PurificationDesc :
Antiserum
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Gene :
FOXC1
StandardGeneSymbol :
FOXC1
gene family :
Transcription factor
Reactivity :
Mouse, Bovine, Rat, Human, Monkey
Usage :
IHC, IHC-P (1:200), WB (1:250 - 1:1000)
ShortWebDescription :
FOXC1 antibody LS-B1800 is an unconjugated rabbit polyclonal antibody to FOXC1 (aa250-300) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB. Cited in 1 publication.
UsageText :
Immunohistochemistry: LS-B1800 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1800 was determined to be 1:200.
Synonyms :
FOXC1, Forkhead-like 7, FREAC3, FKHL7, Forkhead-related activator 3, Forkhead-related protein FKHL7, IGDA, IHG1, IRID1, Forkhead box protein C1, Mesenchyme fork head protein 1, Myeloid factor-delta, ARA, Forkhead box C1, FREAC-3, RIEG3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.