product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ SYCP3 / SCP3 Antibody (C-Terminus) LS-B175
catalog :
LS-B175
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:500; loading ...; fig 2f
Ehrmann I, Crichton J, Gazzara M, James K, Liu Y, Grellscheid S, et al. An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning. elife. 2019;8: pubmed publisher
Reichmann J, Dobie K, Lister L, Crichton J, Best D, Maclennan M, et al. Tex19.1 inhibits the N-end rule pathway and maintains acetylated SMC3 cohesin and sister chromatid cohesion in oocytes. J Cell Biol. 2020;219: pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B175 image 1
Anti-SYCP3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
product information
AntibodyID :
28096
AntibodyName :
LS-B175
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ SYCP3 / SCP3 Antibody (C-Terminus) LS-B175
Specificity :
SCP3.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
PBS, 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A synthetic peptide made to the C-Terminus of the human SCP3 protein.
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze.
Gene :
SYCP3 / SCP3
StandardGeneSymbol :
SYCP3
Reactivity :
Mouse, Bovine, Rat, Pig, Human
Usage :
IF, IHC, IHC-Fr (1:200 - 1:500), IHC-P (20 µg/ml), WB
ShortWebDescription :
SCP3 antibody LS-B175 is an unconjugated rabbit polyclonal antibody to SCP3 (SYCP3) (C-Terminus) from human. It is reactive with human, mouse, rat and other species. Validated for IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
Immunohistochemistry: LS-B175 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B175 was determined to be 20 ug/ml.
Synonyms :
SYCP3, SCP3, SPGF4, Synaptonemal complex protein 3, SCP-3, COR1
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.