product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ SYN / FYN Antibody (aa7-176, clone FYN-59) LS-B1657
catalog :
LS-B1657
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
FYN-59
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Laird R, Laky K, Hayes S. Unexpected role for the B cell-specific Src family kinase B lymphoid kinase in the development of IL-17-producing ?? T cells. J Immunol. 2010;185:6518-27 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B1657 image 1
Anti-FYN antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
image 2 :
LifeSpan Biosciences LS-B1657 image 2
Extracts from human PBMC were resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal antibody against Fyn. Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system.
product information
AntibodyID :
47438
AntibodyName :
LS-B1657
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ SYN / FYN Antibody (aa7-176, clone FYN-59) LS-B1657
Specificity :
Partial recombinant human Fyn (aa 7-176) expressed in E coli
ClonalityDesc :
Monoclonal
CloneName :
FYN-59
AntibodyModification :
Unconjugated
AntigenModification :
aa7-176
PresentationDesc :
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide at 0.5 mg/ml.
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human FYN.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C. Avoid freezing.
IsotypeName :
IgG
Gene :
SYN / FYN
StandardGeneSymbol :
FYN
gene family :
Protein Kinase
Subfamily :
Src
Reactivity :
Mouse, Human
Usage :
IHC, IHC-P (15 µg/ml), IP, WB
ShortWebDescription :
FYN antibody LS-B1657 is an unconjugated mouse monoclonal antibody to FYN (SYN) (aa7-176) from human. It is reactive with human and mouse. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
Immunohistochemistry: LS-B1657 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1657 was determined to be 15 ug/ml.
Synonyms :
FYN, C-syn protooncogene, Fyn kinase, Fyn tyrosine kinase, p59-FYN, SYN, Src-like kinase, Src/yes-related novel, Tyrosine kinase fyn, Tyrosine kinase p59fyn(T), Tyrosine-protein kinase Fyn, Proto-oncogene c-Fyn, Proto-oncogene Syn
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.