IHC-plus™ SREBF2 / SREBP2 Antibody (aa455-469) LS-B1609 | LifeSpan Biosciences LS-B1609 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

IHC-plus™ SREBF2 / SREBP2 Antibody (aa455-469) LS-B1609

catalog :

LS-B1609

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

LifeSpan Biosciences product webpage

citations: 1

Reference
Ferris H, Perry R, Moreira G, Shulman G, Horton J, Kahn C. Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism. Proc Natl Acad Sci U S A. 2017;114:1189-1194 pubmed publisher

image

image 1 :

Anti-SREBP-2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

product information

AntibodyID :

47115

AntibodyName :

LS-B1609

TargetSpecies :

Human

Host Species :

Rabbit

Product Name :

IHC-plus™ SREBF2 / SREBP2 Antibody (aa455-469) LS-B1609

Specificity :

human SREBP-2 amino acids 455-469 (SPLLDDAKVKDEPDS)

ClonalityDesc :

Polyclonal

AntibodyModification :

Unconjugated

AntigenModification :

aa455-469

PresentationDesc :

PBS, pH 7.2, 0.02% Sodium Azide, 50% Glycerol

ImmunogenDesc :

Human SREBP-2 amino acids 455-469 (SPLLDDAKVKDEPDS). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Dog, Bovine, Hamster, Elephant, Panda, Horse, Pig, Turkey, Chicken, Platypus, Lizard (100%); Bat, Xenopus (93%).

PurificationDesc :

Affinity purified

RecommendedStorageDesc :

Aliquot and store at -20°C.

IsotypeName :

IgG

Gene :

SREBF2 / SREBP2

BlockingPeptide :

LS-E47602

StandardGeneSymbol :

SREBF2

Reactivity :

Chicken, Bovine, Rat, Hamster, Pig, Horse, Mouse, Dog, Human, Monkey

Usage :

ICC (1:150), IHC-P (5 µg/ml), WB (1:200)

ShortWebDescription :

SREBP2 antibody LS-B1609 is an unconjugated rabbit polyclonal antibody to SREBP2 (SREBF2) (aa455-469) from human. It is reactive with human, mouse, rat and other species. Validated for ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.

UsageText :

Immunohistochemistry: LS-B1609 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1609 was determined to be 5 ug/ml.

Synonyms :

SREBF2, SREBP2, SREBP-2, BHLHd2

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.