product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ ZFP36 / Tristetraprolin Antibody (aa84-133) LS-B1572
catalog :
LS-B1572
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 3
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 25 ug/ml; loading ...; fig 3
Khalaj K, Luna R, de França M, de Oliveira W, Peixoto C, Tayade C. RNA binding protein, tristetraprolin in a murine model of recurrent pregnancy loss. Oncotarget. 2016;7:72486-72502 pubmed publisher
Ricciardi L, Col J, Casolari P, Memoli D, Conti V, Vatrella A, et al. Differential expression of RNA-binding proteins in bronchial epithelium of stable COPD patients. Int J Chron Obstruct Pulmon Dis. 2018;13:3173-3190 pubmed publisher
Sullivan W, Mullen P, Schmid E, Flores A, Momcilovic M, Sharpley M, et al. Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization. Cell. 2018;175:117-132.e21 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B1572 image 1
Anti-ZFP36 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
product information
AntibodyID :
45507
AntibodyName :
LS-B1572
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ ZFP36 / Tristetraprolin Antibody (aa84-133) LS-B1572
Specificity :
Human ZFP36
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa84-133
PresentationDesc :
PBS, 0.09% sodium azide, 2% sucrose
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide located between aa84-133 of human ZFP36 (P26651, NP_003398). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon (100%); Marmoset, Mouse, Rat, Sheep, Panda, Dog, Bovine, Rabbit, Guinea pig (85%); Elephant (83%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
ZFP36 / Tristetraprolin
BlockingPeptide :
LS-E12181
StandardGeneSymbol :
ZFP36
Reactivity :
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Pig, Human
Usage :
IHC, IHC-P (5 µg/ml), WB (0.2 - 1 µg/ml)
ShortWebDescription :
Tristetraprolin antibody LS-B1572 is an unconjugated rabbit polyclonal antibody to Tristetraprolin (ZFP36) (aa84-133) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
UsageText :
Immunohistochemistry: LS-B1572 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1572 was determined to be 5 ug/ml.
Synonyms :
ZFP36, Protein TIS11A, Tristetraprolin, ZFP36 ring finger protein, TIS11, Zinc finger protein 36 homolog, TTP, NUP475, TIS11A, Tristetraproline, Zfp-36, G0S24, GOS24, RNF162A
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.