product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ ARRB1 + ARRB2 Antibody LS-B15546
catalog :
LS-B15546
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 1
Reference
Luessen D, Sun H, McGinnis M, Hagstrom M, MARRS G, McCool B, et al. Acute ethanol exposure reduces serotonin receptor 1A internalization by increasing ubiquitination and degradation of β-arrestin2. J Biol Chem. 2019;294:14068-14080 pubmed publisher
product information
AntibodyID :
697179
AntibodyName :
LS-B15546
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ ARRB1 + ARRB2 Antibody LS-B15546
Specificity :
The antibody detects recombinant rat and human beta-arrestin and beta-arrestin2. This antibody does not detect visual or cone arrestin. It has been successfully used in Western blot, Immunohistochemistry (paraffin) and immunoprecipitation procedures. By Western blot, this antibody detects ~49 kD and ~47 kD proteins representing recombinant beta-arrestin and beta-arrestin2, respectively.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 1 mg/ml BSA, 0.05% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to aa384-397 (DDIVFEDFARLRLK). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Galago, Mouse, Rat, Bovine, Hamster, Panda, Xenopus, Zebrafish (100%); Drosophila, Mosquito, Beetle (93%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
ARRB1 + ARRB2
StandardGeneSymbol :
ARRB1 + ARRB2
Reactivity :
Xenopus, Zebrafish, Rat, Hamster, Mouse, Bovine, Human, Monkey, Gibbon
Usage :
IHC, IHC-P (5 µg/ml), IP, WB (3 µg/ml)
ShortWebDescription :
ARRB1 + ARRB2 antibody LS-B15546 is an unconjugated rabbit polyclonal antibody to ARRB1 + ARRB2 from human. It is reactive with human, mouse, rat and other species. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Synonyms :
, ARRB1 + ARRB2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.