product summary
Loading...
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ TLR8 Antibody LS-B1421
catalog :
LS-B1421
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 1
Reference
Zheng N, Xie K, Ye H, Dong Y, Wang B, Luo N, et al. TLR7 in B cells promotes renal inflammation and Gd-IgA1 synthesis in IgA nephropathy. JCI Insight. 2020;5: pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B1421 image 1
Anti-TLR8 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
image 2 :
LifeSpan Biosciences LS-B1421 image 2
Immunofluorescence of TLR8 in Daudi cells with TLR8 antibody at 10 ug/ml.
product information
AntibodyID :
40206
AntibodyName :
LS-B1421
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ TLR8 Antibody LS-B1421
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS containing 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A peptide corresponding to 16 AA near the middle of human TLR8. The immunogen is located within aa 790-840 of TLR8.
PurificationDesc :
Peptide Column Affinity Chromatography
RecommendedStorageDesc :
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
TLR8
BlockingPeptide :
LS-E30059
StandardGeneSymbol :
TLR8
gene family :
Toll-like Receptor
Reactivity :
Mouse, Human
Usage :
ELISA, ICC, IF, IHC, IHC-P (5 µg/ml), WB (0.5 - 2 µg/ml)
ShortWebDescription :
TLR8 antibody LS-B1421 is an unconjugated rabbit polyclonal antibody to TLR8 from human. It is reactive with human and mouse. Validated for ELISA, ICC, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
TLR8 antibody can be used for detection of TLR8 by Western blot at 0.5 to 2 ug/mL. Antibody can also be used for immunocytochemistry starting at 2 ug/mL. For immunofluorescence start at 10 ug/mL. Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Western Blot: Predicted: 112 kDa Observed: 107 kDa
Synonyms :
TLR8, CD288, Toll-like receptor 8, CD288 antigen
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.