product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ IRS1 Antibody LS-B1373
catalog :
LS-B1373
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Sposato V, Canu N, Fico E, Fusco S, Bolasco G, Ciotti M, et al. The Medial Septum Is Insulin Resistant in the AD Presymptomatic Phase: Rescue by Nerve Growth Factor-Driven IRS1 Activation. Mol Neurobiol. 2019;56:535-552 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B1373 image 1
Anti-IRS1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
image 2 :
LifeSpan Biosciences LS-B1373 image 2
Immunocytochemistry of IRS-1 in P815 cells with IRS-1 antibody at 2 ug/ml.
image 3 :
LifeSpan Biosciences LS-B1373 image 3
Immunofluorescence of IRS-1 in P815 cells with IRS-1 antibody at 2 ug/ml.
product information
AntibodyID :
40158
AntibodyName :
LS-B1373
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ IRS1 Antibody LS-B1373
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS containing 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A 16 AA synthetic peptide near the center of human IRS-1. The immunogen is located within aa 910-960 of IRS-1.
PurificationDesc :
Peptide Column Affinity Chromatography
RecommendedStorageDesc :
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
IRS1
BlockingPeptide :
LS-E30145
StandardGeneSymbol :
IRS1
Reactivity :
Mouse, Human
Usage :
ELISA, ICC, IF, IHC, IHC-P (5 µg/ml), WB (1 - 2 µg/ml)
ShortWebDescription :
IRS1 antibody LS-B1373 is an unconjugated rabbit polyclonal antibody to IRS1 from human. It is reactive with human and mouse. Validated for ELISA, ICC, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
IRS-1antibody can be used for the detection of IRS-1 by Western blot at 1 - 4 ug/mL. Antibody can also be used for immunocytochemistry starting at 2 ug/mL. For immunofluorescence start at 2 ug/mL. Antibody validated: Western Blot in human samples; Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Western Blot:
Synonyms :
IRS1, IRS-1, HIRS-1, Insulin receptor substrate 1
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.