product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ IKBKB / IKK2 / IKK Beta Antibody LS-B1362
catalog :
LS-B1362
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Marino S, Bishop R, Capulli M, Sophocleous A, Logan J, Mollat P, et al. Regulation of breast cancer induced bone disease by cancer-specific IKKβ. Oncotarget. 2018;9:16134-16148 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B1362 image 1
Anti-IKBKB / IKK Beta antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
image 2 :
LifeSpan Biosciences LS-B1362 image 2
Immunofluorescence of IKK beta in HeLa cells with IKK beta antibody at 10 ug/ml.
product information
AntibodyID :
40147
AntibodyName :
LS-B1362
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ IKBKB / IKK2 / IKK Beta Antibody LS-B1362
Specificity :
This polyclonal antibody has no cross response to IKKa or IKKy.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS containing 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A peptide corresponding to amino acids near the C-Terminus of human IKK beta (Genbank accession NoO14920), which differs from corresponding murine sequence by one amino acid. The immunogen is located within aa 650-700 of IKK beta.
PurificationDesc :
Peptide Column Affinity Chromatography
RecommendedStorageDesc :
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
IKBKB / IKK2 / IKK Beta
BlockingPeptide :
LS-E29892
StandardGeneSymbol :
IKBKB
gene family :
Protein Kinase
Subfamily :
IKAPPAB
Reactivity :
Human
Usage :
ELISA, ICC, IF, IHC, IHC-P (5 µg/ml), WB (1:500)
ShortWebDescription :
IKK Beta antibody LS-B1362 is an unconjugated rabbit polyclonal antibody to human IKK Beta (IKBKB / IKK2). Validated for ELISA, ICC, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
IKK beta antibody can be used for detection of IKK beta by Western blot at 0.5 ug/mL. A 87 kDa band should be detected. Antibody can also be used for immunocytochemistry starting at 10 ug/mL. For immunofluorescence start at 10 ug/mL. Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Western Blot: 87 kDa
Synonyms :
IKBKB, Ikk 2, IKK-B, IKK2, IKKbeta, NFKBIKB, I-kappa-B kinase 2, IKKB, I-kappa-B-kinase beta, Ikb kinase-beta, IKK Beta, IKK-beta
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.