This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ GAPDH Antibody (clone 4G5) LS-B11581
catalog :
LS-B11581
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4G5

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
341198
AntibodyName :
LS-B11581
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ GAPDH Antibody (clone 4G5) LS-B11581
Specificity :
Recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyze the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin.
ClonalityDesc :
Monoclonal
CloneName :
4G5
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, less than 0.1% Sodium Azide
ImmunogenType :
Native protein
ImmunogenDesc :
Human cardiac muscle GADPH.
PurificationDesc :
Protein A purified from ascites
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
GAPDH
StandardGeneSymbol :
GAPDH
Reactivity :
Human
Usage :
ELISA, IF, IHC, IHC-Fr, IHC-P (5 - 10 µg/ml), IP, WB
ShortWebDescription :
GAPDH antibody LS-B11581 is an unconjugated mouse monoclonal antibody to human GAPDH. Validated for ELISA, IF, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Synonyms :
GAPDH, A1 40 kd subunit, Activator 1 40 kd subunit, G3PD, GAPD, G3pdh, Rfc40, Rf-c 40 kd subunit
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.