product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ OSMR / IL-31R-Beta Antibody (aa612-661) LS-B11477
catalog :
LS-B11477
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 1
Reference
Hashimoto T, Nattkemper L, Kim H, Kursewicz C, Fowler E, Shah S, et al. Dermal Periostin: A New Player in Itch of Prurigo Nodularis. Acta Derm Venereol. 2021;101:adv00375 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B11477 image 1
Anti-OSMR antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
product information
AntibodyID :
341007
AntibodyName :
LS-B11477
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ OSMR / IL-31R-Beta Antibody (aa612-661) LS-B11477
Specificity :
Human OSMR
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa612-661
PresentationDesc :
PBS, 0.09% sodium azide, 2% sucrose
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide located between aa612-661 of human OSMR (Q99650, NP_003990). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Dog, Horse, Guinea pig (100%); Elephant (92%); Rabbit (91%); Galago (85%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
OSMR / IL-31R-Beta
BlockingPeptide :
LS-E16913
StandardGeneSymbol :
OSMR
Reactivity :
Dog, Guinea pig, Horse, Human, Monkey
Usage :
IHC, IHC-P (10 µg/ml), WB (0.2 - 1 µg/ml)
ShortWebDescription :
IL-31R-Beta antibody LS-B11477 is an unconjugated rabbit polyclonal antibody to IL-31R-Beta (OSMR) (aa612-661) from human. It is reactive with human, dog, guinea pig and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
Western Blot: Suggested dilution at 1µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:312500.
Synonyms :
OSMR, IL-31R-beta, IL-31R subunit beta, PLCA1, Oncostatin M receptor, OSMRB, IL-31 receptor subunit beta, IL-31RB
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.