product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ LMNB1 / Lamin B1 Antibody (aa526-537) LS-B11184
catalog :
LS-B11184
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
. Multisystem proteinopathy due to a homozygous p.Arg159His VCP mutation: A tale of the unexpected. Neurology. 2020;94:e785-e796 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B11184 image 1
LMNB1 antibody (1 ug/ml) staining of nuclear HeLa lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
image 2 :
LifeSpan Biosciences LS-B11184 image 2
Anti-LMNB1 / Lamin B1 antibody IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
product information
AntibodyID :
321870
AntibodyName :
LS-B11184
TargetSpecies :
Human
Host Species :
Goat
Product Name :
IHC-plus™ LMNB1 / Lamin B1 Antibody (aa526-537) LS-B11184
Specificity :
Human LMNB1 / Lamin B1. This antibody is expected to recognize both reported isoforms (NP_005564.1; NP_001185486.1).
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa526-537
PresentationDesc :
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
ImmunogenDesc :
Peptide with sequence C-DVKVILKNSQGE, from the internal region (near C-Terminus) of the protein sequence according to NP_005564.1NP_001185486.1.
PurificationDesc :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
RecommendedStorageDesc :
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Gene :
LMNB1 / Lamin B1
BlockingPeptide :
LS-E27951
StandardGeneSymbol :
LMNB1
Reactivity :
Mouse, Dog, Bovine, Pig, Human
Usage :
IHC, IHC-P (5 µg/ml), Peptide-ELISA (1:4000), WB (1 - 3 µg/ml)
ShortWebDescription :
Lamin B1 antibody LS-B11184 is an unconjugated goat polyclonal antibody to Lamin B1 (LMNB1) (aa526-537) from human. It is reactive with human, mouse, bovine and other species. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 70kD band observed in nuclear lysates of cell lines HeLa and Jurkat (calculated MW of 66.4kD according to NP_005564.1). Recommended concentration: 0.3-1 ug/ml.
Synonyms :
LMNB1, ADLD, Lamin B1, Lamin-B1, LMN, LMNB, LMN2
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.