product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ CXCR3 Antibody LS-B10183
catalog :
LS-B10183
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Ngwenyama N, Salvador A, Velazquez F, NEVERS T, Levy A, Aronovitz M, et al. CXCR3 regulates CD4+ T cell cardiotropism in pressure overload-induced cardiac dysfunction. JCI Insight. 2019;4: pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B10183 image 1
Anti-CXCR3 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
image 2 :
LifeSpan Biosciences LS-B10183 image 2
Western blot analysis of CXCR3 in HepG2 lysate with CXCR3 antibody at (A) 1 and (B) 2 ug/ml.
image 3 :
LifeSpan Biosciences LS-B10183 image 3
Immunocytochemistry of CXCR3 in HepG2 cells with CXCR3 antibody at 5 µg/mL.
product information
AntibodyID :
294768
AntibodyName :
LS-B10183
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ CXCR3 Antibody LS-B10183
Specificity :
CXCR3 antibody is human, mouse and rat reactive. At least two isoforms of CXCR3 are known to exist; this antibody will detect both isoforms.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS containing 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A 19 amino acid peptide near the C-Terminus of human CXCR3 . The immunogen is located within the last 50 amino acids of CXCR3.
PurificationDesc :
Peptide Column Affinity Chromatography
RecommendedStorageDesc :
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
CXCR3
BlockingPeptide :
LS-E45896
StandardGeneSymbol :
CXCR3
gene family :
GPCR
Subfamily :
Chemokine
Reactivity :
Mouse, Rat, Human
Usage :
ELISA, ICC, IF, IHC, IHC-P (10 µg/ml), WB (1 - 2 µg/ml)
ShortWebDescription :
CXCR3 antibody LS-B10183 is an unconjugated rabbit polyclonal antibody to CXCR3 from human. It is reactive with human, mouse and rat. Validated for ELISA, ICC, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
CXCR3 antibody can be used for detection of CXCR3 by Western blot at 1 - 2 ug/ml. Antibody can also be used for Immunocytochemistry at 5 ug/mL. For Immunoflorescence start at 20 ug/mL. Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Western Blot: Predicted: 46 kDa Observed: 43 kDa
Synonyms :
CXCR3, C-x-c chemokine receptor 3, CD183 antigen, CKR-L2, CXCR-3, CMKAR3, CD182, CD183, Cxcr3a, GPR9, IP-10 receptor, IP10-R, Mig receptor, MigR, Mig-R, Chemokine (C-X-C) receptor 3, CXC-R3, Cxcr3b, G protein-coupled receptor 9, IP10 receptor
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.