product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ MAP3K11 / MLK3 Antibody (clone 3D11) LS-B10053
catalog :
LS-B10053
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3D11
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunohistochemistry - frozen section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; human
Krauthammer M, Kong Y, Ha B, Evans P, Bacchiocchi A, McCusker J, et al. Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat Genet. 2012;44:1006-14 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B10053 image 1
Western blot of MAP3K11 expression in transfected 293T cell line by MAP3K11 monoclonal antibody, clone 3D11. Lane 1: MAP3K11 transfected lysate(92.7 KDa).Lane 2: Non-transfected lysate.
image 2 :
LifeSpan Biosciences LS-B10053 image 2
IHC with MAP3K11 antibody on frozen human spleen.
image 3 :
LifeSpan Biosciences LS-B10053 image 3
Detection limit for recombinant GST tagged MAP3K11 is 0.1 ng/ml as a capture antibody.
product information
AntibodyID :
240987
AntibodyName :
LS-B10053
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ MAP3K11 / MLK3 Antibody (clone 3D11) LS-B10053
Specificity :
Human MAP3K11
ClonalityDesc :
Monoclonal
CloneName :
3D11
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.4
ImmunogenType :
Recombinant protein
ImmunogenDesc :
MAP3K11 (NP_002410, 741 aa ~ 848 aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
PurificationDesc :
Purified from ascites by Protein A
RecommendedStorageDesc :
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
IsotypeName :
IgG2a,k
Gene :
MAP3K11 / MLK3
StandardGeneSymbol :
MAP3K11
gene family :
Protein Kinase
Subfamily :
MLK(MAP3K)
Reactivity :
Human
Usage :
ELISA, IHC, IHC-Fr (1:50), WB
UsageNotRecommended :
IHC-P
ShortWebDescription :
MLK3 antibody LS-B10053 is an unconjugated mouse monoclonal antibody to human MLK3 (MAP3K11). Validated for ELISA, IHC and WB. Tested on 20 human tissues. Cited in 1 publication.
UsageText :
Western Blot: Transfected lysate, Recombinant protein.
Synonyms :
MAP3K11, Mixed lineage kinase 3, MLK3, Protein-tyrosine kinase PTK1, PTK1, SPRK, MLK-3, MEKK11
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.