product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PathPlus™ c-Kit / CD117 Antibody (Extracellular Domain) LS-A9389
catalog :
LS-A9389
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 2d
Maehara T, Munemura R, Shimizu M, Kakizoe N, Kaneko N, Murakami Y, et al. Tissue-infiltrating immune cells contribute to understanding the pathogenesis of Kimura disease: A case report. Medicine (Baltimore). 2019;98:e18300 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-A9389 image 1
Anti-c-Kit antibody IHC of human spleen, central artery and lymphocytes within periarteriolar lymphoid sheaths. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
product information
AntibodyID :
19884
AntibodyName :
LS-A9389
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
PathPlus™ c-Kit / CD117 Antibody (Extracellular Domain) LS-A9389
Specificity :
Human c-Kit. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
Extracellular Domain
PresentationDesc :
PBS, 0.1% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic 16 amino acid peptide from extracellular domain of human c-Kit. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Monkey (94%); Marmoset, Mouse, Rat (88%); Hamster, Pig (81%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Gene :
c-Kit / CD117
BlockingPeptide :
LS-E29627
StandardGeneSymbol :
KIT
gene family :
Protein Kinase
Subfamily :
PDGF Receptor
Reactivity :
Human
Usage :
IHC, IHC-P (20 µg/ml)
ShortWebDescription :
CD117 antibody LS-A9389 is an unconjugated rabbit polyclonal antibody to human CD117 (c-Kit) (Extracellular Domain). Validated for IHC. Cited in 1 publication.
UsageText :
Immunohistochemistry: The unconjugated form was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for the unconjugated form was determined to be 20 ug/ml.
Synonyms :
KIT, C-Kit, CD117, PBT, Piebald trait, Piebald trait protein, Proto-oncogene c-Kit, SCFR, Soluble KIT variant 1, Tyrosine-protein kinase Kit, p145 c-kit, CD117 antigen
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.