product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ MTNR1B / MT2 Antibody (N-Terminus) LS-A930
catalog :
LS-A930
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
DEVORE E, Warner E, Eliassen A, Brown S, Beck A, Hankinson S, et al. Urinary Melatonin in Relation to Postmenopausal Breast Cancer Risk According to Melatonin 1 Receptor Status. Cancer Epidemiol Biomarkers Prev. 2017;26:413-419 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-A930 image 1
Anti-MTNR1B antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
product information
AntibodyID :
2081
AntibodyName :
LS-A930
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ MTNR1B / MT2 Antibody (N-Terminus) LS-A930
Specificity :
Human MTNR1B. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NEURL1B (56%).
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminus
PresentationDesc :
PBS, 0.1% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic 16 amino acid peptide from N-Terminus extracellular domain of human MTNR1B. Percent identity with other species by BLAST analysis: Human (100%); Gorilla (94%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Gene :
MTNR1B / MT2
BlockingPeptide :
LS-E29602
StandardGeneSymbol :
MTNR1B
gene family :
GPCR
Subfamily :
Melatonin
Reactivity :
Human
Usage :
ELISA, IHC, IHC-P (10 µg/ml)
ShortWebDescription :
MT2 antibody LS-A930 is an unconjugated rabbit polyclonal antibody to human MT2 (MTNR1B) (N-Terminus). Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
Immunohistochemistry: The unconjugated form was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for the unconjugated form was determined to be 10 ug/ml.
Synonyms :
MTNR1B, MEL-1B-R, Mel-1b melatonin receptor, Melatonin receptor 1B, Melatonin receptor MEL1B, Mt2r, MT2 melatonin receptor, MtT2 receptor, Melatonin receptor type 1B, MT2, FGQTL2, Mel1b receptor
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.