product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ PDE3A Antibody (N-Terminus) LS-A732
catalog :
LS-A732
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 5a
  • immunohistochemistry; human
Mahmood B, Damm M, Jensen T, Backe M, Dahllöf M, Poulsen S, et al. Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia. BMC Cancer. 2016;16:938 pubmed
image
image 1 :
LifeSpan Biosciences LS-A732 image 1
Anti-PDE3A antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
product information
AntibodyID :
3211
AntibodyName :
LS-A732
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ PDE3A Antibody (N-Terminus) LS-A732
Specificity :
Human PDE3A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminus
PresentationDesc :
PBS, 0.1% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic 18 amino acid peptide from N-Terminus of human PDE3A. Percent identity with other species by BLAST analysis: Human (100%); Gibbon, Monkey (94%); Horse (83%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Gene :
PDE3A
BlockingPeptide :
LS-E29253
StandardGeneSymbol :
PDE3A
gene family :
Phosphodiesterase
Subfamily :
PDE - cAMP/cGMP dual-specific, cGMP-inhibited
Reactivity :
Human
Usage :
IHC, IHC-P (20 µg/ml)
ShortWebDescription :
PDE3A antibody LS-A732 is an unconjugated rabbit polyclonal antibody to human PDE3A (N-Terminus). Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
Immunohistochemistry: The unconjugated form was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for the unconjugated form was determined to be 20 ug/ml.
Synonyms :
PDE3A, CGI-PDE-A, HcGIP2, Phosphodiesterase 3a, Phosphodiesterase isoform 3a, CGI-PDE, CGI-PDE A, CGIP2, HPDE-3A, Phosphodiesterase type 3A
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.