product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PathPlus™ GPER1 / GPR30 Antibody (C-Terminus) LS-A4272
catalog :
LS-A4272
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Reference
Pupo M, Bodmer A, Berto M, Maggiolini M, Dietrich P, Picard D. A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells. Oncotarget. 2017;8:46728-46744 pubmed publisher
Umar S, Partow Navid R, Ruffenach G, Iorga A, Moazeni S, Eghbali M. Severe pulmonary hypertension in aging female apolipoprotein E-deficient mice is rescued by estrogen replacement therapy. Biol Sex Differ. 2017;8:9 pubmed publisher
product information
AntibodyID :
1560
AntibodyName :
LS-A4272
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
PathPlus™ GPER1 / GPR30 Antibody (C-Terminus) LS-A4272
Specificity :
Human GPR30. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
PBS, 0.1% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic 18 amino acid peptide from C-Terminus of human GPR30. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Dog (100%); Rat, Horse (94%); Mouse, Hamster (89%); Elephant, Bovine (83%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Gene :
GPER1 / GPR30
BlockingPeptide :
LS-E28933
StandardGeneSymbol :
GPER1
gene family :
GPCR
Subfamily :
Transmembrane Estrogen Receptor
Reactivity :
Dog, Rat, Human, Monkey
Usage :
IF, IHC, IHC-Fr, IHC-P (5 - 10 µg/ml), WB
ShortWebDescription :
GPR30 antibody LS-A4272 is an unconjugated rabbit polyclonal antibody to GPR30 (GPER1) (C-Terminus) from human. It is reactive with human, rat, dog and other species. Validated for IF, IHC and WB. Cited in 9 publications.
Synonyms :
GPER1, CMKRL2, CEPR, FEG-1, G-protein coupled receptor 30, G protein-coupled receptor 30, GPCR-Br, GPER, Heptahelix receptor, LERGU, LyGPR, MER, GPR30, IL8-related receptor DRY12, LERGU2, Chemokine receptor-like 2, DRY12, Membrane estrogen receptor
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.