product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ GPR68 / OGR1 Antibody (N-Terminus) LS-A3968
catalog :
LS-A3968
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Xu J, Mathur J, Vessieres E, Hammack S, Nonomura K, Favre J, et al. GPR68 Senses Flow and Is Essential for Vascular Physiology. Cell. 2018;173:762-775.e16 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-A3968 image 1
Anti-GPR68 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
product information
AntibodyID :
1473
AntibodyName :
LS-A3968
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ GPR68 / OGR1 Antibody (N-Terminus) LS-A3968
Specificity :
Human GPR68. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminus
PresentationDesc :
PBS, 0.1% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic 17 amino acid peptide from N-Terminus of human GPR68. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Bat, Elephant, Horse (100%); Marmoset, Mouse, Rat, Dog, Hamster, Rabbit, Pig (94%); Bovine, Panda (88%); Platypus (82%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Gene :
GPR68 / OGR1
BlockingPeptide :
LS-E28854
StandardGeneSymbol :
GPR68
gene family :
GPCR
Subfamily :
Lysophospholipid/Lysosphingolipid
Reactivity :
Horse, Bat, Human
Usage :
ELISA, IHC, IHC-P (5 - 10 µg/ml)
ShortWebDescription :
OGR1 antibody LS-A3968 is an unconjugated rabbit polyclonal antibody to OGR1 (GPR68) (N-Terminus) from human. It is reactive with human, bat and horse. Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues.
UsageText :
Immunohistochemistry: The unconjugated form was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for the unconjugated form was determined to be 5-10 ug/ml.Antibody does not work for IHC with mouse samples.
Synonyms :
GPR68, Brgrb, G protein-coupled receptor 68, G-protein coupled receptor 68, OGR1, Brgr1, GPR12A, OGR-1
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.