product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PathPlus™ SMO / Smoothened Antibody (1st Extracellular Domain) LS-A2668
catalog :
LS-A2668
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 1
Reference
Lüdtke T, Rudat C, Kurz J, Häfner R, Greulich F, Wojahn I, et al. Mesothelial mobilization in the developing lung and heart differs in timing, quantity, and pathway dependency. Am J Physiol Lung Cell Mol Physiol. 2019;316:L767-L783 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-A2668 image 1
Anti-SMO / Smoothened antibody IHC of human Skin, Basal Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
product information
AntibodyID :
187429
AntibodyName :
LS-A2668
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
PathPlus™ SMO / Smoothened Antibody (1st Extracellular Domain) LS-A2668
Specificity :
Human SMO. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
1st Extracellular Domain
PresentationDesc :
PBS, 0.1% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic 16 amino acid peptide from 1st extracellular domain of human SMO. Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey (100%); Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Pig, Turkey, Chicken, Platypus, Xenopus (94%); Opossum (88%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Gene :
SMO / Smoothened
BlockingPeptide :
LS-E28592
StandardGeneSymbol :
SMO
gene family :
GPCR
Subfamily :
Frizzled
Reactivity :
Mouse, Human
Usage :
IF, IHC, IHC-P (1:400)
ShortWebDescription :
Smoothened antibody LS-A2668 is an unconjugated rabbit polyclonal antibody to Smoothened (SMO) (1st Extracellular Domain) from human. It is reactive with human and mouse. Validated for IF and IHC. Cited in 5 publications.
Synonyms :
SMO, Frizzled family member 11, FZD11, Gx, Protein Gx, SMOH, Smoothened, Smoothened homolog
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.