product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ XCR1 Antibody (Extracellular Domain) LS-A158
catalog :
LS-A158
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Bird E, Iannitti T, Christmas C, Obara I, Andreev V, King A, et al. A Novel Role for Lymphotactin (XCL1) Signaling in the Nervous System: XCL1 Acts via its Receptor XCR1 to Increase Trigeminal Neuronal Excitability. Neuroscience. 2018;379:334-349 pubmed publisher
product information
AntibodyID :
938
AntibodyName :
LS-A158
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ XCR1 Antibody (Extracellular Domain) LS-A158
Specificity :
Human XCR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
Extracellular Domain
PresentationDesc :
PBS, 0.1% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic 19 amino acid peptide from 3rd extracellular domain of human XCR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey (89%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Gene :
XCR1
BlockingPeptide :
LS-E28336
StandardGeneSymbol :
XCR1
gene family :
GPCR
Subfamily :
Chemokine
Reactivity :
Human
Usage :
IHC, IHC-P (2.5 µg/ml)
ShortWebDescription :
XCR1 antibody LS-A158 is an unconjugated rabbit polyclonal antibody to human XCR1 (Extracellular Domain). Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
Immunohistochemistry: The unconjugated form was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for the unconjugated form was determined to be 2.5 ug/ml.
Synonyms :
XCR1, CCXCR1, Chemokine (C motif) receptor 1, Chemokine XC receptor 1, G protein-coupled receptor 5, GPR5, Lptn receptor, Lymphotactin receptor, XC chemokine receptor 1, G-protein coupled receptor 5
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.