product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PathPlus™ LPAR3 / LPA3 / EDG7 Antibody (Cytoplasmic Domain) LS-A1014
catalog :
LS-A1014
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
citations: 2
Reference
Chabowski D, Kadlec A, Ait Aissa K, Hockenberry J, Pearson P, Beyer A, et al. Lysophosphatidic acid acts on LPA1 receptor to increase H2 O2 during flow-induced dilation in human adipose arterioles. Br J Pharmacol. 2018;175:4266-4280 pubmed publisher
Yang B, Wang L, Wan X, Li Y, Yu X, Qin Y, et al. Elevated plasma levels of lysophosphatidic acid and aberrant expression of lysophosphatidic acid receptors in adenomyosis. BMC Womens Health. 2017;17:118 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-A1014 image 1
Anti-LPAR3 / LPA3 / EDG7 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
product information
AntibodyID :
3069
AntibodyName :
LS-A1014
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
PathPlus™ LPAR3 / LPA3 / EDG7 Antibody (Cytoplasmic Domain) LS-A1014
Specificity :
Human EDG7. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
Cytoplasmic Domain
PresentationDesc :
PBS, 0.1% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human EDG7. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Horse, Opossum, Platypus (100%); Panda (94%); Pig, Turkey, Chicken (88%); Xenopus (81%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Gene :
LPAR3 / LPA3 / EDG7
BlockingPeptide :
LS-E28095
StandardGeneSymbol :
LPAR3
gene family :
GPCR
Subfamily :
Lysophospholipid/Lysosphingolipid
Reactivity :
Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
Usage :
IHC, IHC-P (10 µg/ml)
ShortWebDescription :
EDG7 antibody LS-A1014 is an unconjugated rabbit polyclonal antibody to EDG7 (LPAR3 / LPA3) (Cytoplasmic Domain) from human. It is reactive with human, mouse, rat and other species. Validated for IHC. Cited in 3 publications.
Synonyms :
LPAR3, EDG7, Edg-7, LPA receptor 3, HOFNH30, LPA3, RP4-678I3, LP-A3, LPA receptor EDG7, LPA-3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.