product summary
company name :
Leica Biosystems
other brands :
Novocastra, Surgipath
product type :
antibody
product name :
emerin
catalog :
NCL-EMERIN
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4G5
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:300; loading ...; fig 4b
O'Grady G, Best H, Sztal T, Schartner V, Sanjuan-Vazquez M, Donkervoort S, et al. Variants in the Oxidoreductase PYROXD1 Cause Early-Onset Myopathy with Internalized Nuclei and Myofibrillar Disorganization. Am J Hum Genet. 2016;99:1086-1105 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 2
  • western blot; human; 1:500; fig 9
Eisch V, Lu X, Gabriel D, Djabali K. Progerin impairs chromosome maintenance by depleting CENP-F from metaphase kinetochores in Hutchinson-Gilford progeria fibroblasts. Oncotarget. 2016;7:24700-18 pubmed publisher
  • immunocytochemistry; mouse; 1:50; fig s2d
Fuchs C, Gawlas S, Heher P, Nikouli S, Paar H, Ivankovic M, et al. Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene. Biol Open. 2016;5:140-53 pubmed publisher
  • western blot; mouse; 1:5000
Tapia O, Fong L, Huber M, Young S, Gerace L. Nuclear envelope protein Lem2 is required for mouse development and regulates MAP and AKT kinases. PLoS ONE. 2015;10:e0116196 pubmed publisher
  • immunohistochemistry; mouse; 1:200
Jung H, Tatar A, Tu Y, Nobumori C, Yang S, Goulbourne C, et al. An absence of nuclear lamins in keratinocytes leads to ichthyosis, defective epidermal barrier function, and intrusion of nuclear membranes and endoplasmic reticulum into the nuclear chromatin. Mol Cell Biol. 2014;34:4534-44 pubmed publisher
Vaajanen A, Kalesnykas G, Vapaatalo H, Uusitalo H. The expression of Mas-receptor of the renin-angiotensin system in the human eye. Graefes Arch Clin Exp Ophthalmol. 2015;253:1053-9 pubmed publisher
Mewborn S, Puckelwartz M, Abuisneineh F, Fahrenbach J, Zhang Y, MacLeod H, et al. Altered chromosomal positioning, compaction, and gene expression with a lamin A/C gene mutation. PLoS ONE. 2010;5:e14342 pubmed publisher
Verstraeten V, Caputo S, van Steensel M, Duband-Goulet I, Zinn-Justin S, Kamps M, et al. The R439C mutation in LMNA causes lamin oligomerization and susceptibility to oxidative stress. J Cell Mol Med. 2009;13:959-71 pubmed publisher
Boudreau E, Labib S, Bertrand A, Decostre V, Bolongo P, Sylvius N, et al. Lamin A/C mutants disturb sumo1 localization and sumoylation in vitro and in vivo. PLoS ONE. 2012;7:e45918 pubmed publisher
Ho C, Jaalouk D, Vartiainen M, Lammerding J. Lamin A/C and emerin regulate MKL1-SRF activity by modulating actin dynamics. Nature. 2013;497:507-11 pubmed publisher
product information
product code :
NCL-EMERIN
product name :
emerin
application :
IHCP
more info or order :
company information
Leica Biosystems
hrna@leica-microsystems.com
www.leicabiosystems.com