product summary
company name :
Leica Biosystems
other brands :
Novocastra, Surgipath
product type :
antibody
product name :
CD 163, Macrophage-associated antigen
catalog :
NCL-CD163
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 2g
Pascual García M, Bonfill Teixidor E, Planas Rigol E, Rubio Perez C, Iurlaro R, Arias A, et al. LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy. Nat Commun. 2019;10:2416 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 4e
Zrzavy T, Hoftberger R, Berger T, Rauschka H, Butovsky O, Weiner H, et al. Pro-inflammatory activation of microglia in the brain of patients with sepsis. Neuropathol Appl Neurobiol. 2019;45:278-290 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 4d
Maliniemi P, Laukkanen K, Väkevä L, Dettmer K, Lipsanen T, Jeskanen L, et al. Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas. Oncoimmunology. 2017;6:e1273310 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 2f
Burgess M, Mapp S, Mazzieri R, Cheung C, Chambers L, Mattarollo S, et al. Increased FcγRIIB dominance contributes to the emergence of resistance to therapeutic antibodies in chronic lymphocytic leukaemia patients. Oncogene. 2017;36:2366-2376 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; fig s2
Chen P, Roh W, Reuben A, Cooper Z, Spencer C, Prieto P, et al. Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade. Cancer Discov. 2016;6:827-37 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 1
Jhaveri K, Teplinsky E, Silvera D, Valeta Magara A, Arju R, Giashuddin S, et al. Hyperactivated mTOR and JAK2/STAT3 Pathways: Molecular Drivers and Potential Therapeutic Targets of Inflammatory and Invasive Ductal Breast Cancers After Neoadjuvant Chemotherapy. Clin Breast Cancer. 2016;16:113-22.e1 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 2
Zeineh M, Chen Y, Kitzler H, Hammond R, Vogel H, Rutt B. Activated iron-containing microglia in the human hippocampus identified by magnetic resonance imaging in Alzheimer disease. Neurobiol Aging. 2015;36:2483-500 pubmed publisher
Zeiner P, Preusse C, Golebiewska A, Zinke J, Iriondo A, Muller A, et al. Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas. Brain Pathol. 2019;29:513-529 pubmed publisher
Camisaschi C, Renne S, Beretta V, Rini F, Spagnuolo R, Tuccitto A, et al. Immune landscape and in vivo immunogenicity of NY-ESO-1 tumor antigen in advanced neuroblastoma patients. BMC Cancer. 2018;18:983 pubmed publisher
Zrzavy T, Machado Santos J, Christine S, Baumgartner C, Weiner H, Butovsky O, et al. Dominant role of microglial and macrophage innate immune responses in human ischemic infarcts. Brain Pathol. 2017;: pubmed publisher
Furukawa S, Moriyama M, Miyake K, Nakashima H, Tanaka A, Maehara T, et al. Interleukin-33 produced by M2 macrophages and other immune cells contributes to Th2 immune reaction of IgG4-related disease. Sci Rep. 2017;7:42413 pubmed publisher
Dalloneau E, Baroukh N, Mavridis K, Maillet A, Gueugnon F, Courty Y, et al. Downregulation of the neonatal Fc receptor expression in non-small cell lung cancer tissue is associated with a poor prognosis. Oncotarget. 2016;7:54415-54429 pubmed publisher
Carpino G, Nobili V, Renzi A, De Stefanis C, Stronati L, Franchitto A, et al. Macrophage Activation in Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) Correlates with Hepatic Progenitor Cell Response via Wnt3a Pathway. PLoS ONE. 2016;11:e0157246 pubmed publisher
Hollmen M, Karaman S, Schwager S, Lisibach A, Christiansen A, Maksimow M, et al. G-CSF regulates macrophage phenotype and associates with poor overall survival in human triple-negative breast cancer. Oncoimmunology. 2016;5:e1115177 pubmed
Olmes G, Büttner Herold M, Ferrazzi F, Distel L, Amann K, Daniel C. CD163+ M2c-like macrophages predominate in renal biopsies from patients with lupus nephritis. Arthritis Res Ther. 2016;18:90 pubmed publisher
Lundholm M, Hägglöf C, Wikberg M, Stattin P, Egevad L, Bergh A, et al. Secreted Factors from Colorectal and Prostate Cancer Cells Skew the Immune Response in Opposite Directions. Sci Rep. 2015;5:15651 pubmed publisher
Tudor C, Bruns H, Daniel C, Distel L, Hartmann A, Gerbitz A, et al. Macrophages and dendritic cells as actors in the immune reaction of classical Hodgkin lymphoma. PLoS ONE. 2014;9:e114345 pubmed publisher
Castelli C, Tazzari M, Negri T, Vergani B, Rivoltini L, Stacchiotti S, et al. Structured myeloid cells and anti-angiogenic therapy in alveolar soft part sarcoma. J Transl Med. 2013;11:237 pubmed publisher
Fischer M, Wimmer I, Hoftberger R, Gerlach S, Haider L, Zrzavy T, et al. Disease-specific molecular events in cortical multiple sclerosis lesions. Brain. 2013;136:1799-815 pubmed publisher
Gelman B, Chen T, Lisinicchia J, Soukup V, Carmical J, Starkey J, et al. The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment. PLoS ONE. 2012;7:e46178 pubmed publisher
Haniffa M, Ginhoux F, Wang X, Bigley V, Abel M, Dimmick I, et al. Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation. J Exp Med. 2009;206:371-85 pubmed publisher
company information
Leica Biosystems
hrna@leica-microsystems.com
http://www.leicabiosystems.com