Reference |
---|
Suwala A, Koch K, Rios D, Aretz P, Uhlmann C, Ogorek I, et al. Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro. Oncotarget. 2018;9:22703-22716 pubmed publisher
|
Qiao L, Zheng J, Tian Y, Zhang Q, Wang X, Chen J, et al. Regulator of chromatin condensation 1 abrogates the G1 cell cycle checkpoint via Cdk1 in human papillomavirus E7-expressing epithelium and cervical cancer cells. Cell Death Dis. 2018;9:583 pubmed publisher
|
Mir R, Tonelli F, Lis P, MacArtney T, Polinski N, Martinez T, et al. The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human. Biochem J. 2018;475:1861-1883 pubmed publisher
|
Lai S, Phelps C, Short A, Dutta S, Mu D. Thyroid transcription factor 1 enhances cellular statin sensitivity via perturbing cholesterol metabolism. Oncogene. 2018;37:3290-3300 pubmed publisher
|
Filippini A, Bonini D, Giacopuzzi E, La Via L, Gangemi F, Colombi M, et al. Differential Enzymatic Activity of Rat ADAR2 Splicing Variants Is Due to Altered Capability to Interact with RNA in the Deaminase Domain. Genes (Basel). 2018;9: pubmed publisher
|
Ran L, Chen Y, Sher J, Wong E, Murphy D, Zhang J, et al. FOXF1 Defines the Core-Regulatory Circuitry in Gastrointestinal Stromal Tumor. Cancer Discov. 2018;8:234-251 pubmed publisher
|
Rodero M, Tesser A, Bartok E, Rice G, Della Mina E, Depp M, et al. Type I interferon-mediated autoinflammation due to DNase II deficiency. Nat Commun. 2017;8:2176 pubmed publisher
|
Volanakis A, Kamieniarz Gdula K, Schlackow M, Proudfoot N. WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcription. Genes Dev. 2017;31:2175-2185 pubmed publisher
|
Girnius N, Davis R. JNK Promotes Epithelial Cell Anoikis by Transcriptional and Post-translational Regulation of BH3-Only Proteins. Cell Rep. 2017;21:1910-1921 pubmed publisher
|
Court H, Ahearn I, Amoyel M, Bach E, Philips M. Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT. J Cell Biol. 2017;216:4165-4182 pubmed publisher
|
Tian F, Yuan C, Hu L, Shan S. MicroRNA-93 inhibits inflammatory responses and cell apoptosis after cerebral ischemia reperfusion by targeting interleukin-1 receptor-associated kinase 4. Exp Ther Med. 2017;14:2903-2910 pubmed publisher
|
Gillen A, Brechbuhl H, Yamamoto T, Kline E, Pillai M, Hesselberth J, et al. Alternative Polyadenylation of PRELID1 Regulates Mitochondrial ROS Signaling and Cancer Outcomes. Mol Cancer Res. 2017;15:1741-1751 pubmed publisher
|
Beaufils F, Cmiljanovic N, Cmiljanovic V, Bohnacker T, Melone A, Marone R, et al. 5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine (PQR309), a Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class I PI3K/mTOR Inhibitor as Clinical Candidate in Oncology. J Med Chem. 2017;60:7524-7538 pubmed publisher
|
Pengo N, Agrotis A, Prak K, Jones J, Ketteler R. A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B. Nat Commun. 2017;8:294 pubmed publisher
|
Han C, Zeng X, Yao S, Gao L, Zhang L, Qi X, et al. Voltage-Dependent Anion Channel 1 Interacts with Ribonucleoprotein Complexes To Enhance Infectious Bursal Disease Virus Polymerase Activity. J Virol. 2017;91: pubmed publisher
|
Zou Z, Meng Z, Ma C, Liang D, Sun R, Lan K. Guanylate-Binding Protein 1 Inhibits Nuclear Delivery of Kaposi's Sarcoma-Associated Herpesvirus Virions by Disrupting Formation of Actin Filament. J Virol. 2017;91: pubmed publisher
|
King B, Hershkowitz D, Eisenhauer P, Weir M, Ziegler C, Russo J, et al. A Map of the Arenavirus Nucleoprotein-Host Protein Interactome Reveals that JunÃn Virus Selectively Impairs the Antiviral Activity of Double-Stranded RNA-Activated Protein Kinase (PKR). J Virol. 2017;91: pubmed publisher
|
Ashkenazi A, Bento C, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, et al. Polyglutamine tracts regulate beclin 1-dependent autophagy. Nature. 2017;545:108-111 pubmed publisher
|
Edens L, Dilsaver M, Levy D. PKC-mediated phosphorylation of nuclear lamins at a single serine residue regulates interphase nuclear size in Xenopus and mammalian cells. Mol Biol Cell. 2017;28:1389-1399 pubmed publisher
|
Bohnacker T, Prota A, Beaufils F, Burke J, Melone A, Inglis A, et al. Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention. Nat Commun. 2017;8:14683 pubmed publisher
|
Holland W, Xia J, Johnson J, Sun K, Pearson M, Sharma A, et al. Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis. Mol Metab. 2017;6:267-275 pubmed publisher
|
Duan T, Sun W, Zhang M, Ge J, He Y, Zhang J, et al. Dietary restriction protects against diethylnitrosamine-induced hepatocellular tumorigenesis by restoring the disturbed gene expression profile. Sci Rep. 2017;7:43745 pubmed publisher
|
Ho T, Warr M, Adelman E, Lansinger O, Flach J, Verovskaya E, et al. Autophagy maintains the metabolism and function of young and old stem cells. Nature. 2017;543:205-210 pubmed publisher
|
Welsch M, Kaplan A, Chambers J, Stokes M, Bos P, Zask A, et al. Multivalent Small-Molecule Pan-RAS Inhibitors. Cell. 2017;168:878-889.e29 pubmed publisher
|
Kuintzle R, Chow E, Westby T, Gvakharia B, Giebultowicz J, Hendrix D. Circadian deep sequencing reveals stress-response genes that adopt robust rhythmic expression during aging. Nat Commun. 2017;8:14529 pubmed publisher
|
Sethna F, Feng W, Ding Q, ROBISON A, Feng Y, Wang H. Enhanced expression of ADCY1 underlies aberrant neuronal signalling and behaviour in a syndromic autism model. Nat Commun. 2017;8:14359 pubmed publisher
|
Dingjan I, Linders P, van den Bekerom L, Baranov M, Halder P, ter Beest M, et al. Oxidized phagosomal NOX2 complex is replenished from lysosomes. J Cell Sci. 2017;130:1285-1298 pubmed publisher
|
Wang J, Yu Y, Lu K, Yang M, Li Y, Zhou X, et al. Silica nanoparticles induce autophagy dysfunction via lysosomal impairment and inhibition of autophagosome degradation in hepatocytes. Int J Nanomedicine. 2017;12:809-825 pubmed publisher
|
Zhu C, Yu Y, Montani J, Ming X, Yang Z. Arginase-I enhances vascular endothelial inflammation and senescence through eNOS-uncoupling. BMC Res Notes. 2017;10:82 pubmed publisher
|
Huber F, Hoelz A. Molecular basis for protection of ribosomal protein L4 from cellular degradation. Nat Commun. 2017;8:14354 pubmed publisher
|
Thompson A, Metzger S, Lochner M, Ruepp M. The binding orientation of epibatidine at α7 nACh receptors. Neuropharmacology. 2017;116:421-428 pubmed publisher
|
Zazo Seco C, Castells Nobau A, Joo S, Schraders M, Foo J, van der Voet M, et al. A homozygous FITM2 mutation causes a deafness-dystonia syndrome with motor regression and signs of ichthyosis and sensory neuropathy. Dis Model Mech. 2017;10:105-118 pubmed publisher
|
Richardson R, Batchen E, Thomson A, Darroch R, Pan X, Rog Zielinska E, et al. Glucocorticoid receptor alters isovolumetric contraction and restrains cardiac fibrosis. J Endocrinol. 2017;232:437-450 pubmed publisher
|
Bronckers A, Jalali R, Lytton J. Reduced Protein Expression of the Na+/Ca2++K+-Exchanger (SLC24A4) in Apical Plasma Membranes of Maturation Ameloblasts of Fluorotic Mice. Calcif Tissue Int. 2017;100:80-86 pubmed publisher
|
Chen L, Weinmeister R, Kralovicova J, Eperon L, Vorechovsky I, Hudson A, et al. Stoichiometries of U2AF35, U2AF65 and U2 snRNP reveal new early spliceosome assembly pathways. Nucleic Acids Res. 2017;45:2051-2067 pubmed publisher
|
O Neill A, Kindberg A, Niethamer T, Larson A, Ho H, Greenberg M, et al. Unidirectional Eph/ephrin signaling creates a cortical actomyosin differential to drive cell segregation. J Cell Biol. 2016;215:217-229 pubmed
|
Guiney E, Klecker T, Emr S. Identification of the endocytic sorting signal recognized by the Art1-Rsp5 ubiquitin ligase complex. Mol Biol Cell. 2016;27:4043-4054 pubmed
|
Guimarães T, Farias L, Santos E, De Carvalho Fraga C, Orsini L, de Freitas Teles L, et al. Metformin increases PDH and suppresses HIF-1? under hypoxic conditions and induces cell death in oral squamous cell carcinoma. Oncotarget. 2016;7:55057-55068 pubmed publisher
|
Freund P, Porpaczy E, Le T, Gruber M, Pausz C, Staber P, et al. Cannabinoid Receptors Are Overexpressed in CLL but of Limited Potential for Therapeutic Exploitation. PLoS ONE. 2016;11:e0156693 pubmed publisher
|
Zuckermann A, La Ragione R, Baines D, Williams R. Valproic acid protects against haemorrhagic shock-induced signalling changes via PPARγ activation in an in vitro model. Br J Pharmacol. 2015;172:5306-17 pubmed publisher
|