GENLISA™ Mouse IL - 6 ELISA | Krishgen Biosystems KB2068 product information

product summary

company name :

Krishgen Biosystems

product type :

ELISA/assay

product name :

GENLISA™ Mouse IL - 6 ELISA

catalog :

KB2068

quantity :

1 x 96 wells

price :

270 USD

more info or order :

Krishgen Biosystems product webpage

citations: 39

Reference
Tripathi S, Kumar R, Bissoyi A, Rizvi S. Baicalein maintains redox balance in experimental hyperlipidemic rats. Arch Physiol Biochem. 2022;128:1156-1164 pubmed publisher
Gouthamchandra K, Sudeep H, Chandrappa S, Raj A, Naveen P, Shyamaprasad K. Efficacy of a Standardized Turmeric Extract Comprised of 70% Bisdemothoxy-Curcumin (REVERC3) Against LPS-Induced Inflammation in RAW264.7 Cells and Carrageenan-Induced Paw Edema. J Inflamm Res. 2021;14:859-868 pubmed publisher
Barve K. Garcinol enriched fraction from the fruit rind of Garcinia indica ameliorates atherosclerotic risk factor in diet induced hyperlipidemic C57BL/6 mice. J Tradit Complement Med. 2021;11:95-102 pubmed publisher
Kamdi S, Raval A, Nakhate K. Phloridzin attenuates lipopolysaccharide-induced cognitive impairment via antioxidant, anti-inflammatory and neuromodulatory activities. Cytokine. 2021;139:155408 pubmed publisher
Srinivasan A, Aruldhas J, Perumal S, Ekambaram S. Phenolic acid bound arabinoxylans extracted from Little and Kodo millets modulate immune system mediators and pathways in RAW 264.7 cells. J Food Biochem. 2021;45:e13563 pubmed publisher
Tripathi S, Kumar R, Arya J, Rizvi S. Plasma from Young Rats Injected into Old Rats Induce Antiaging Effects. Rejuvenation Res. 2021;24:206-212 pubmed publisher
Kesherwani R, Kumar R, Minhas U, Rizvi S. Euglena tuba extract provides protection against lipopolysaccharide-induced inflammatory response and oxidative stress in mice. Biologia (Bratisl). 2021;76:793-798 pubmed publisher
Singla E, Puri G, Dharwal V, Naura A. Gallic acid ameliorates COPD-associated exacerbation in mice. Mol Cell Biochem. 2021;476:293-302 pubmed publisher
Zameer S, Ali J, Vohora D, Najmi A, Akhtar M. Development, optimisation and evaluation of chitosan nanoparticles of alendronate against Alzheimer's disease in intracerebroventricular streptozotocin model for brain delivery. J Drug Target. 2021;29:199-216 pubmed publisher
Apaydin Yildirim B, Aydin T, Kordali S, Yildirim S, Cakir A, Yildirim F. Antihemorrhoidal activity of organic acids of Capsella bursa-pastoris on croton oil-induced hemorrhoid in rats. J Food Biochem. 2020;44:e13343 pubmed publisher
Ingawale D, Mandlik S, Patel S. Combination of Sarsasapogenin and Fluticasone attenuates ovalbumin-induced airway inflammation in a mouse asthma model. Immunopharmacol Immunotoxicol. 2020;42:128-137 pubmed publisher
Chandra K, Jain V, Jabin A, Dwivedi S, Joshi S, Ahmad S, et al. Effect of Cichorium intybus seeds supplementation on the markers of glycemic control, oxidative stress, inflammation, and lipid profile in type 2 diabetes mellitus: A randomized, double-blind placebo study. Phytother Res. 2020;34:1609-1618 pubmed publisher
Puri G, Naura A. Critical role of mitochondrial oxidative stress in acid aspiration induced ALI in mice. Toxicol Mech Methods. 2020;30:266-274 pubmed publisher
Hirudkar J, Parmar K, Prasad R, Sinha S, Jogi M, Itankar P, et al. Quercetin a major biomarker of Psidium guajava L. inhibits SepA protease activity of Shigella flexneri in treatment of infectious diarrhoea. Microb Pathog. 2020;138:103807 pubmed publisher
Ekambaram S, Perumal S, Erusappan T, Srinivasan A. Hydrolysable tannin-rich fraction from Terminalia chebula Retz. fruits ameliorates collagen-induced arthritis in BALB/c mice. Inflammopharmacology. 2020;28:275-287 pubmed publisher
Iqubal A, Sharma S, Najmi A, Syed M, Ali J, Alam M, et al. Nerolidol ameliorates cyclophosphamide-induced oxidative stress, neuroinflammation and cognitive dysfunction: Plausible role of Nrf2 and NF- κB. Life Sci. 2019;236:116867 pubmed publisher
Azeemuddin M, Rao C, Rafiq M, Babu U, Rangesh P. Pharmacological investigation of 'HIM-CHX': A herbal combination in the experimental muscle wasting condition. Exp Gerontol. 2019;125:110663 pubmed publisher
Sharma Y, Ahmad A, Yavvari P, Kumar Muwal S, Bajaj A, Khan F. Targeted SHP-1 Silencing Modulates the Macrophage Phenotype, Leading to Metabolic Improvement in Dietary Obese Mice. Mol Ther Nucleic Acids. 2019;16:626-636 pubmed publisher
Ingawale D, Mandlik S, Patel S. Anti-inflammatory potential of hecogenin on atopic dermatitis and airway hyper-responsiveness by regulation of pro-inflammatory cytokines. Immunopharmacol Immunotoxicol. 2019;41:327-336 pubmed publisher
Singh G, Kaur A, Kaur J, Bhatti M, Singh P, Bhatti R. Bergapten inhibits chemically induced nociceptive behavior and inflammation in mice by decreasing the expression of spinal PARP, iNOS, COX-2 and inflammatory cytokines. Inflammopharmacology. 2019;: pubmed publisher
Nigam K, Kaur A, Tyagi A, Nematullah M, Khan F, Gabrani R, et al. Nose-to-brain delivery of lamotrigine-loaded PLGA nanoparticles. Drug Deliv Transl Res. 2019;: pubmed publisher
Das M, Solanki A, Joshi A, Devkar R, Seshadri S, Thakore S. β-cyclodextrin based dual-responsive multifunctional nanotheranostics for cancer cell targeting and dual drug delivery. Carbohydr Polym. 2019;206:694-705 pubmed publisher
Zameer S, Kaundal M, Vohora D, Ali J, Kalam Najmi A, Akhtar M. Ameliorative effect of alendronate against intracerebroventricular streptozotocin induced alteration in neurobehavioral, neuroinflammation and biochemical parameters with emphasis on Aβ and BACE-1. Neurotoxicology. 2019;70:122-134 pubmed publisher
Nandeesh R, Vijayakumar S, Munnolli A, Alreddy A, Veerapur V, Chandramohan V, et al. Bioactive phenolic fraction of Citrus maxima abate lipopolysaccharide-induced sickness behaviour and anorexia in mice: In-silico molecular docking and dynamic studies of biomarkers against NF-κB. Biomed Pharmacother. 2018;108:1535-1545 pubmed publisher
Iqubal A, Sharma S, Sharma K, Bhavsar A, Hussain I, Iqubal M, et al. Intranasally administered pitavastatin ameliorates pentylenetetrazol-induced neuroinflammation, oxidative stress and cognitive dysfunction. Life Sci. 2018;211:172-181 pubmed publisher
S M, T P, Goli D. Effect of wedelolactone and gallic acid on quinolinic acid-induced neurotoxicity and impaired motor function: significance to sporadic amyotrophic lateral sclerosis. Neurotoxicology. 2018;68:1-12 pubmed publisher
Singh G, Bhatti R, Mannan R, Singh D, Kesavan A, Singh P. Osthole ameliorates neurogenic and inflammatory hyperalgesia by modulation of iNOS, COX-2, and inflammatory cytokines in mice. Inflammopharmacology. 2018;: pubmed publisher
Chowdhury A, Gawali N, Shinde P, Munshi R, Juvekar A. Imperatorin ameliorates lipopolysaccharide induced memory deficit by mitigating proinflammatory cytokines, oxidative stress and modulating brain-derived neurotropic factor. Cytokine. 2018;110:78-86 pubmed publisher
Sharma S, Kumar P, Deshmukh R. Neuroprotective potential of spermidine against rotenone induced Parkinson's disease in rats. Neurochem Int. 2018;116:104-111 pubmed publisher
Shukla G, Sharma A, Bhatia R, Sharma M. Prophylactic Potential of Synbiotic (Lactobacillus casei and Inulin) in Malnourished Murine Giardiasis: an Immunological and Ultrastructural Study. Probiotics Antimicrob Proteins. 2019;11:165-174 pubmed publisher
Ingawale D, Patel S. Hecogenin exhibits anti-arthritic activity in rats through suppression of pro-inflammatory cytokines in Complete Freund's adjuvant-induced arthritis. Immunopharmacol Immunotoxicol. 2017;:1-13 pubmed publisher
Singh S, Jamwal S, Kumar P. Neuroprotective potential of Quercetin in combination with piperine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. Neural Regen Res. 2017;12:1137-1144 pubmed publisher
Sharma Y, Bashir S, Ansarullah -, Faraz Khan M, Ahmad A, Khan F. Inhibition of Src homology 2 domain containing protein tyrosine phosphatase as the possible mechanism of metformin-assisted amelioration of obesity induced insulin resistance in high fat diet fed C57BL/6J mice. Biochem Biophys Res Commun. 2017;487:54-61 pubmed publisher
Akyol A, Kavak E, Akyol H, Pala x, G xfc rsu F. The Non-Ergot Derived Dopamine Agonist Quinagolide as an Anti-Endometriotic Agent. Gynecol Obstet Invest. 2017;82:527-532 pubmed publisher
Jagtap S, Khare P, Mangal P, Kondepudi K, Bishnoi M, Bhutani K. Effect of mahanimbine, an alkaloid from curry leaves, on high-fat diet-induced adiposity, insulin resistance, and inflammatory alterations. Biofactors. 2017;43:220-231 pubmed publisher
Hagawane T, Gaikwad R, Kshirsagar N. Dual hit lipopolysaccharide & oleic acid combination induced rat model of acute lung injury/acute respiratory distress syndrome. Indian J Med Res. 2016;143:624-32 pubmed publisher
Dey Y, Wanjari M, Kumar D, Lomash V, Jadhav A. Curative effect of Amorphophallus paeoniifolius tuber on experimental hemorrhoids in rats. J Ethnopharmacol. 2016;192:183-191 pubmed publisher
Kumar N, Rai A, Reddy N, Raj P, Jain P, Deshpande P, et al. Silymarin liposomes improves oral bioavailability of silybin besides targeting hepatocytes, and immune cells. Pharmacol Rep. 2014;66:788-98 pubmed publisher
Mathew G, Jacob A, Durgashivaprasad E, Reddy N, Unnikrishnan M. 6b,11b-Dihydroxy-6b,11b-dihydro-7H-indeno[1,2-b]naphtho[2,1-d]furan-7-one (DHFO), a small molecule targeting NF-?B, demonstrates therapeutic potential in immunopathogenic chronic inflammatory conditions. Int Immunopharmacol. 2013;15:182-9 pubmed publisher

product information

Catalog Number :

KB2068

Product Name :

GENLISA™ Mouse IL - 6 ELISA

Product Type :

ELISA

Size :

1 x 96 wells

List Price (USD) :

270 USD

Product Description :

This ELISA is intended for the quantitative detection of IL-6 in mouse serum, cell cuture supernatant and plasma samples. ELISA Features include:- Ready to use protocol, Standardisation and High Reproducibility, Lot to Lot Consistency, Accuracy and Precision. Validated against seven points for a Gold Ring Standard Quality ELISA - the benchmark sign for Krishgen quality, Long shelf-life, Expert technical support. The GENLISA ELISA kits are used for assessing the specific biomarker in samples analytes which may be serum, plasma, biological fluids and cell culture supernatant. The kit employs a double-antibody sandwich ELISA technique which leads to higher specificity and increased sensitivity compared to conventional competitive ELISA kits which employ only one antibody.

SpeciesSummary :

Mouse

Background :

IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells.IL-6 plays a role in host defense, acute phase reactions, immune response, and hematopoiesis. IL-6 is expressed by T cells, B cells, monocytes, fibroblasts, hepatocytes, endothelial cells, and keratinocytes. Recombinant mouse IL-6 is a 21.7 kDa protein containing 187 amino acids.

Packaging :

This ELISA kit comes with a pre-coated plate, concentrated or lyophilized standards, wash solution, subtrate, stop solution and all the required diluents. For the exact contents of the kit, please refer to the datasheet / IFU.

Storage :

2-8 Deg C

Calibration Range :

31.25 pg/ml to 2000 pg/ml

Sensitivity :

21.8 pg/ml

Assay Principle :

The method employs a sandwich ELISA technique. Monoclonal antibodies are pre-coated onto microwells. Samples and standards are pipetted into microwells and analyte present in the sample are bound by the antibodies. Biotin labeled anti-analyte antibodies are added and followed by Streptavidin-HRP pipetting and incubation to form a complex. After washing microwells in order to remove any non-specific binding, the substrate solution (TMB) is added to microwells and color develops proportionally to the amount of analyte in the sample. Color development is then stopped by addition of stop solution. Absorbance is measured at 450 nm.

Biomarker :

IL-6

Regulatory Status :

RUO

Shipping :

2-8 degrees C

more info or order :

Krishgen Biosystems product webpage