product summary
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company name :
Jackson ImmunoResearch Laboratories
product type :
secondary antibody
product name :
Peroxidase AffiniPure™ F(ab')2 fragment Goat Anti-Human IgM, Fc5μ fragment specific (min X Bov Sr Prot)
catalog :
109-036-129
quantity :
0.5 ml
price :
161 USD
citations: 4
Reference
White J, Crossman M, Richter K, Berman M, Goyal J, Subramanyam M. Immunogenicity evaluation strategy for a second-generation therapeutic, PEG-IFN-?-1a. Bioanalysis. 2015;7:2801-11 pubmed publisher
Holland M, Wurthner J, Morley P, Birchler M, Lambert J, Albayaty M, et al. Autoantibodies to variable heavy (VH) chain Ig sequences in humans impact the safety and clinical pharmacology of a VH domain antibody antagonist of TNF-? receptor 1. J Clin Immunol. 2013;33:1192-203 pubmed publisher
Zahorsky Reeves J, Gregory C, Cramer D, Patanwala I, Kyles A, Borie D, et al. Similarities in the immunoglobulin response and VH gene usage in rhesus monkeys and humans exposed to porcine hepatocytes. BMC Immunol. 2006;7:3 pubmed
Liu J, Weintraub A, Holgersson J. Multivalent Galalpha1,3Gal-substitution makes recombinant mucin-immunoglobulins efficient absorbers of anti-pig antibodies. Xenotransplantation. 2003;10:149-63 pubmed
product information
Catalog Number :
109-036-129
Product Name :
Peroxidase AffiniPure™ F(ab')2 fragment Goat Anti-Human IgM, Fc5μ fragment specific (min X Bov Sr Prot)
Product Type :
Secondary Antibody
Host Species :
Goat
Clonality :
Polyclonal
Conjugation :
Horseradish Peroxidase
Size :
0.5 ml
USD List Price :
161 USD
Euro List Price :
213
Product Description :
Based on immunoelectrophoresis and/or ELISA, the antibody reacts with the Fc5mu portion of the human IgM heavy chain but not with human IgG, IgA, or the light chains of human immunoglobulins. No antibody was detected against non-immunoglobulin serum proteins. The antibody has been tested by ELISA and/or solid-phase adsorbed to ensure minimal cross-reaction with bovine serum proteins, but it may cross-react with IgM from other species.
CrossReactivity :
Human
Specificity :
IgM, Fc5µ fragment
company information
Jackson ImmunoResearch Laboratories
872 West Baltimore Pike West Grove, PA, 19390
cuserv@jacksonimmuno.com
http://www.jacksonimmuno.com
1-800-367-5296
headquarters: USA