product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TCR V delta 1 Monoclonal Antibody (TS8.2), FITC
catalog :
TCR2730
quantity :
200 Tests
price :
US 488.00
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
TS8.2
reactivity :
African green monkey, human
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, blocking or activating experiments
more info or order :
citations: 44
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 2a
Mayassi T, Ladell K, Gudjonson H, McLaren J, Shaw D, Tran M, et al. Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease. Cell. 2019;176:967-981.e19 pubmed publisher
  • flow cytometry; human; loading ...; tbl s9
Mordmuller B, Surat G, Lagler H, Chakravarty S, Ishizuka A, Lalremruata A, et al. Sterile protection against human malaria by chemoattenuated PfSPZ vaccine. Nature. 2017;542:445-449 pubmed publisher
  • flow cytometry; human; loading ...; fig 2a
Kim J, Kwon C, Joh J, Sinn D, Choi G, Park J, et al. Differences in Peripheral Blood Lymphocytes between Brand-Name and Generic Tacrolimus Used in Stable Liver Transplant Recipients. Med Princ Pract. 2017;26:221-228 pubmed publisher
  • flow cytometry; human; 1:20; loading ...; fig 5a
Siegers G, Barreira C, Postovit L, Dekaban G. CD11d ?2 integrin expression on human NK, B, and ?? T cells. J Leukoc Biol. 2017;101:1029-1035 pubmed publisher
  • flow cytometry; human; loading ...; fig 2a
Kadivar M, Petersson J, Svensson L, Marsal J. CD8??+ ?? T Cells: A Novel T Cell Subset with a Potential Role in Inflammatory Bowel Disease. J Immunol. 2016;197:4584-4592 pubmed
  • flow cytometry; human; fig 7
Di Marco Barros R, Roberts N, Dart R, Vantourout P, Jandke A, Nussbaumer O, et al. Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments. Cell. 2016;167:203-218.e17 pubmed publisher
  • flow cytometry; human; fig 1
Cimini E, Agrati C, D Offizi G, Vlassi C, Casetti R, Sacchi A, et al. Primary and Chronic HIV Infection Differently Modulates Mucosal Vδ1 and Vδ2 T-Cells Differentiation Profile and Effector Functions. PLoS ONE. 2015;10:e0129771 pubmed publisher
  • flow cytometry; human; fig 3
Oberg H, Kellner C, Gonnermann D, Peipp M, Peters C, Sebens S, et al. γδ T cell activation by bispecific antibodies. Cell Immunol. 2015;296:41-9 pubmed publisher
  • flow cytometry; human; fig 1
Fisher J, Yan M, Heuijerjans J, Carter L, Abolhassani A, Frosch J, et al. Neuroblastoma killing properties of Vδ2 and Vδ2-negative γδT cells following expansion by artificial antigen-presenting cells. Clin Cancer Res. 2014;20:5720-32 pubmed publisher
  • flow cytometry; African green monkey
Hodara V, Parodi L, Chavez D, Smith L, Lanford R, Giavedoni L. Characterization of ??T cells in naïve and HIV-infected chimpanzees and their responses to T-cell activators in vitro. J Med Primatol. 2014;43:258-71 pubmed publisher
  • flow cytometry; human
Oberg H, Peipp M, Kellner C, Sebens S, Krause S, Petrick D, et al. Novel bispecific antibodies increase ?? T-cell cytotoxicity against pancreatic cancer cells. Cancer Res. 2014;74:1349-60 pubmed publisher
  • immunocytochemistry; human
Uldrich A, Le Nours J, Pellicci D, Gherardin N, McPherson K, Lim R, et al. CD1d-lipid antigen recognition by the ?? TCR. Nat Immunol. 2013;14:1137-45 pubmed publisher
  • flow cytometry; human; fig 3
Prinz I, Thamm K, Port M, Weissinger E, Stadler M, Gabaev I, et al. Donor Vδ1+ γδ T cells expand after allogeneic hematopoietic stem cell transplantation and show reactivity against CMV-infected cells but not against progressing B-CLL. Exp Hematol Oncol. 2013;2:14 pubmed publisher
  • flow cytometry; human
Cairo C, Sagnia B, Cappelli G, Colizzi V, Leke R, Leke R, et al. Human cord blood ?? T cells expressing public V?2 chains dominate the response to bisphosphonate plus interleukin-15. Immunology. 2013;138:346-60 pubmed publisher
  • blocking or activating experiments; human; 1 ug/well
  • flow cytometry; human; 1:20
Siegers G, Ribot E, Keating A, Foster P. Extensive expansion of primary human gamma delta T cells generates cytotoxic effector memory cells that can be labeled with Feraheme for cellular MRI. Cancer Immunol Immunother. 2013;62:571-83 pubmed publisher
  • immunoprecipitation; human
Dai Y, Chen H, Mo C, Cui L, He W. Ectopically expressed human tumor biomarker MutS homologue 2 is a novel endogenous ligand that is recognized by human ?? T cells to induce innate anti-tumor/virus immunity. J Biol Chem. 2012;287:16812-9 pubmed publisher
  • immunohistochemistry; human
Dimova T, Nagaeva O, Stenqvist A, Hedlund M, Kjellberg L, Strand M, et al. Maternal Foxp3 expressing CD4+ CD25+ and CD4+ CD25- regulatory T-cell populations are enriched in human early normal pregnancy decidua: a phenotypic study of paired decidual and peripheral blood samples. Am J Reprod Immunol. 2011;66 Suppl 1:44-56 pubmed publisher
  • flow cytometry; human
Barakonyi A, Miko E, Varga P, Szekeres Bartho J. V-chain preference of gamma/delta T-cell receptors in peripheral blood during term labor. Am J Reprod Immunol. 2008;59:201-5 pubmed publisher
  • flow cytometry; human
Green A, Lissina A, Hutchinson S, Hewitt R, Temple B, James D, et al. Recognition of nonpeptide antigens by human V gamma 9V delta 2 T cells requires contact with cells of human origin. Clin Exp Immunol. 2004;136:472-82 pubmed
Yu E, Wang E, Garrigan E, Sutherland A, Khalil N, Kearns K, et al. Ex vivo assays show human gamma-delta T cells specific for common allergens are Th1-polarized in allergic donors. Cell Rep Methods. 2022;2:100350 pubmed publisher
Liechti T, Iftikhar Y, Mangino M, Beddall M, Goss C, O Halloran J, et al. Immune phenotypes that are associated with subsequent COVID-19 severity inferred from post-recovery samples. Nat Commun. 2022;13:7255 pubmed publisher
Wang Y, Yang H, Jia A, Wang Y, Yang Q, Dong Y, et al. Dendritic cell Piezo1 directs the differentiation of TH1 and Treg cells in cancer. elife. 2022;11: pubmed publisher
Zarobkiewicz M, Morawska I, Kowalska W, Halczuk P, Roli x144 ski J, Bojarska Junak A. PECAM-1 Is Down-Regulated in γδT Cells during Remission, but Up-Regulated in Relapse of Multiple Sclerosis. J Clin Med. 2022;11: pubmed publisher
Teramo A, Binatti A, Ciabatti E, Schiavoni G, Tarrini G, Baril xe0 G, et al. Defining TCRγδ lymphoproliferative disorders by combined immunophenotypic and molecular evaluation. Nat Commun. 2022;13:3298 pubmed publisher
Seki D, Mayer M, Hausmann B, Pjevac P, Giordano V, Goeral K, et al. Aberrant gut-microbiota-immune-brain axis development in premature neonates with brain damage. Cell Host Microbe. 2021;29:1558-1572.e6 pubmed publisher
Wragg K, Tan H, Kristensen A, Nguyen Robertson C, Kelleher A, Parsons M, et al. High CD26 and Low CD94 Expression Identifies an IL-23 Responsive Vδ2+ T Cell Subset with a MAIT Cell-like Transcriptional Profile. Cell Rep. 2020;31:107773 pubmed publisher
Lo Presti E, Mocciaro F, Mitri R, Corsale A, Di Simone M, Vieni S, et al. Analysis of colon-infiltrating γδ T cells in chronic inflammatory bowel disease and in colitis-associated cancer. J Leukoc Biol. 2020;108:749-760 pubmed publisher
Oll Hurtado M, Wolbert J, Fisher J, Flutter B, Stafford S, Barton J, et al. Tumor infiltrating lymphocytes expanded from pediatric neuroblastoma display heterogeneity of phenotype and function. PLoS ONE. 2019;14:e0216373 pubmed publisher
Olson G, Moore S, Richter J, Garber J, Bowman B, Rawlings C, et al. Increased frequency of systemic pro-inflammatory Vδ1+ γδ T cells in HIV elite controllers correlates with gut viral load. Sci Rep. 2018;8:16471 pubmed publisher
Benyamine A, Magalon J, Sabatier F, Lyonnet L, Robert S, Dumoulin C, et al. Natural Killer Cells Exhibit a Peculiar Phenotypic Profile in Systemic Sclerosis and Are Potent Inducers of Endothelial Microparticles Release. Front Immunol. 2018;9:1665 pubmed publisher
Frasca D, Diaz A, Romero M, Thaller S, Blomberg B. Secretion of autoimmune antibodies in the human subcutaneous adipose tissue. PLoS ONE. 2018;13:e0197472 pubmed publisher
Li Z, Lu X, Hu Z, Luo Z, Jiang W, Wu H, et al. Syphilis Infection Differentially Regulates the Phenotype and Function of γδ T Cells in HIV-1-Infected Patients Depends on the HIV-1 Disease Stage. Front Immunol. 2017;8:991 pubmed publisher
Bao Y, Guo L, Mo J. Characterization of γδ T cells in patients with non-small cell lung cancer. Oncol Lett. 2017;14:1133-1140 pubmed publisher
Barisa M, Kramer A, Majani Y, Moulding D, Saraiva L, Bajaj Elliott M, et al. E. coli promotes human Vγ9Vδ2 T cell transition from cytokine-producing bactericidal effectors to professional phagocytic killers in a TCR-dependent manner. Sci Rep. 2017;7:2805 pubmed publisher
Fisher J, Flutter B, Wesemann F, Frosch J, Rossig C, Gustafsson K, et al. Effective combination treatment of GD2-expressing neuroblastoma and Ewing's sarcoma using anti-GD2 ch14.18/CHO antibody with Vγ9Vδ2+ γδT cells. Oncoimmunology. 2016;5:e1025194 pubmed
Gonnermann D, Oberg H, Kellner C, Peipp M, Sebens S, Kabelitz D, et al. Resistance of cyclooxygenase-2 expressing pancreatic ductal adenocarcinoma cells against γδ T cell cytotoxicity. Oncoimmunology. 2015;4:e988460 pubmed
Mao Y, Yin S, Zhang J, Hu Y, Huang B, Cui L, et al. A new effect of IL-4 on human γδ T cells: promoting regulatory Vδ1 T cells via IL-10 production and inhibiting function of Vδ2 T cells. Cell Mol Immunol. 2016;13:217-28 pubmed publisher
Chen M, Hu P, Ling N, Peng H, Lei Y, Hu H, et al. Enhanced functions of peripheral γδ T cells in chronic hepatitis B infection during interferon α treatment in vivo and in vitro. PLoS ONE. 2015;10:e0120086 pubmed publisher
Li Z, Jiao Y, Hu Y, Cui L, Chen D, Wu H, et al. Distortion of memory Vδ2 γδ T cells contributes to immune dysfunction in chronic HIV infection. Cell Mol Immunol. 2015;12:604-14 pubmed publisher
Ribot J, Ribeiro S, Correia D, Sousa A, Silva Santos B. Human ?? thymocytes are functionally immature and differentiate into cytotoxic type 1 effector T cells upon IL-2/IL-15 signaling. J Immunol. 2014;192:2237-43 pubmed publisher
Marischen L, Wesch D, Schroder J, Wiedow O, Kabelitz D. Human gammadelta T cells produce the protease inhibitor and antimicrobial peptide elafin. Scand J Immunol. 2009;70:547-52 pubmed publisher
Poles M, Barsoum S, Yu W, Yu J, Sun P, Daly J, et al. Human immunodeficiency virus type 1 induces persistent changes in mucosal and blood gammadelta T cells despite suppressive therapy. J Virol. 2003;77:10456-67 pubmed
Brandes M, Willimann K, Lang A, Nam K, Jin C, Brenner M, et al. Flexible migration program regulates gamma delta T-cell involvement in humoral immunity. Blood. 2003;102:3693-701 pubmed
Martini F, Urso R, Gioia C, De Felici A, Narciso P, Amendola A, et al. gammadelta T-cell anergy in human immunodeficiency virus-infected persons with opportunistic infections and recovery after highly active antiretroviral therapy. Immunology. 2000;100:481-6 pubmed
product information
Product Type :
Antibody
Product Name :
TCR V delta 1 Monoclonal Antibody (TS8.2), FITC
Catalog # :
TCR2730
Quantity :
200 Tests
Price :
US 488.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 1-2 ug/test
Species :
Human
Clone :
TS8.2
Isotype :
IgG1
Storage :
4 C, store in dark
Description :
The T Cell Receptor gamma-delta (TCR gamma delta) is a heterodimeric membrane receptor that consists of the highly variable gamma and delta chains expressed as part of a complex with the invariant CD3 proteins. Gamma-delta T cells are less frequent than alpha-beta T cells but compose a substantial part of T cells found at epithelial borders including the gut mucosa resident intraepithelial lymphocytes (IEL). The antigenic stimuli required for gamma-delta T cell receptor activation are not well understood and are thought to be mainly MHC class-independent.
Immunogen :
Human TCR V delta 1
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1-2 ug/test
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA