TCR V delta 1 Monoclonal Antibody (TS8.2) | Invitrogen TCR1730 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TCR V delta 1 Monoclonal Antibody (TS8.2)

catalog :

TCR1730

quantity :

200 ug

price :

US 502.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TS8.2

reactivity :

African green monkey, human, chimpanzee, rhesus macaque

application :

ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments

more info or order :

Invitrogen product webpage

citations: 31

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 0.3 ug/ml; loading ...; fig 1h	Le Nours J, Gherardin N, Ramarathinam S, Awad W, Wiede F, Gully B, et al. A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1. Science. 2019;366:1522-1527 pubmed publisher
flow cytometry; human; loading ...; fig 2a	Kim J, Kwon C, Joh J, Sinn D, Choi G, Park J, et al. Differences in Peripheral Blood Lymphocytes between Brand-Name and Generic Tacrolimus Used in Stable Liver Transplant Recipients. Med Princ Pract. 2017;26:221-228 pubmed publisher
flow cytometry; human; 1:20; loading ...; fig 5a	Siegers G, Barreira C, Postovit L, Dekaban G. CD11d ?2 integrin expression on human NK, B, and ?? T cells. J Leukoc Biol. 2017;101:1029-1035 pubmed publisher
flow cytometry; human; fig S1	Yin W, Tong S, Zhang Q, Shao J, Liu Q, Peng H, et al. Functional dichotomy of Vδ2 γδ T cells in chronic hepatitis C virus infections: role in cytotoxicity but not for IFN-γ production. Sci Rep. 2016;6:26296 pubmed publisher
flow cytometry; human; fig 1, 3	Roy S, Ly D, Castro C, Li N, Hawk A, Altman J, et al. Molecular Analysis of Lipid-Reactive VÎ´1 Î³Î´ T Cells Identified by CD1c Tetramers. J Immunol. 2016;196:1933-42 pubmed publisher
flow cytometry; human	Chen M, Hu P, Ling N, Peng H, Lei Y, Hu H, et al. Enhanced functions of peripheral Î³Î´ T cells in chronic hepatitis B infection during interferon Î± treatment in vivo and in vitro. PLoS ONE. 2015;10:e0120086 pubmed publisher
flow cytometry; human	Li Z, Li W, Li N, Jiao Y, Chen D, Cui L, et al. Î³Î´ T cells are involved in acute HIV infection and associated with AIDS progression. PLoS ONE. 2014;9:e106064 pubmed publisher
flow cytometry; chimpanzee flow cytometry; African green monkey	Hodara V, Parodi L, Chavez D, Smith L, Lanford R, Giavedoni L. Characterization of ??T cells in naïve and HIV-infected chimpanzees and their responses to T-cell activators in vitro. J Med Primatol. 2014;43:258-71 pubmed publisher
flow cytometry; human	Oberg H, Peipp M, Kellner C, Sebens S, Krause S, Petrick D, et al. Novel bispecific antibodies increase ?? T-cell cytotoxicity against pancreatic cancer cells. Cancer Res. 2014;74:1349-60 pubmed publisher
flow cytometry; human	Cairo C, Longinaker N, Cappelli G, Leke R, Ondo M, Djokam R, et al. Cord blood V?2V?2 T cells provide a molecular marker for the influence of pregnancy-associated malaria on neonatal immunity. J Infect Dis. 2014;209:1653-62 pubmed publisher
immunocytochemistry; human	Uldrich A, Le Nours J, Pellicci D, Gherardin N, McPherson K, Lim R, et al. CD1d-lipid antigen recognition by the ?? TCR. Nat Immunol. 2013;14:1137-45 pubmed publisher
flow cytometry; rhesus macaque	Chen C, Yao S, Huang D, Wei H, Sicard H, Zeng G, et al. Phosphoantigen/IL2 expansion and differentiation of V?2V?2 T cells increase resistance to tuberculosis in nonhuman primates. PLoS Pathog. 2013;9:e1003501 pubmed publisher
flow cytometry; human	Cairo C, Sagnia B, Cappelli G, Colizzi V, Leke R, Leke R, et al. Human cord blood ?? T cells expressing public V?2 chains dominate the response to bisphosphonate plus interleukin-15. Immunology. 2013;138:346-60 pubmed publisher
blocking or activating experiments; human; 1 ug/well flow cytometry; human; 1:20	Siegers G, Ribot E, Keating A, Foster P. Extensive expansion of primary human gamma delta T cells generates cytotoxic effector memory cells that can be labeled with Feraheme for cellular MRI. Cancer Immunol Immunother. 2013;62:571-83 pubmed publisher
immunoprecipitation; human	Dai Y, Chen H, Mo C, Cui L, He W. Ectopically expressed human tumor biomarker MutS homologue 2 is a novel endogenous ligand that is recognized by human ?? T cells to induce innate anti-tumor/virus immunity. J Biol Chem. 2012;287:16812-9 pubmed publisher
immunohistochemistry; human	Dimova T, Nagaeva O, Stenqvist A, Hedlund M, Kjellberg L, Strand M, et al. Maternal Foxp3 expressing CD4+ CD25+ and CD4+ CD25- regulatory T-cell populations are enriched in human early normal pregnancy decidua: a phenotypic study of paired decidual and peripheral blood samples. Am J Reprod Immunol. 2011;66 Suppl 1:44-56 pubmed publisher
immunohistochemistry; human	Berti E, Recalcati S, Girgenti V, Fanoni D, Venegoni L, Vezzoli P. Cutaneous extranodal NK/T-cell lymphoma: a clinicopathologic study of 5 patients with array-based comparative genomic hybridization. Blood. 2010;116:165-70 pubmed publisher
flow cytometry; human	Eberl M, Roberts G, Meuter S, Williams J, Topley N, Moser B. A rapid crosstalk of human gammadelta T cells and monocytes drives the acute inflammation in bacterial infections. PLoS Pathog. 2009;5:e1000308 pubmed publisher
flow cytometry; human	Bryant N, Suarez Cuervo C, Gillespie G, Markert J, Nabors L, Meleth S, et al. Characterization and immunotherapeutic potential of gammadelta T-cells in patients with glioblastoma. Neuro Oncol. 2009;11:357-67 pubmed publisher
flow cytometry; human	Futagbi G, Welbeck J, Tetteh J, Hviid L, Akanmori B. Selective activation of TCR-gammadelta+ cells in endemic Burkitt's lymphoma. Malar J. 2007;6:69 pubmed
ELISA; human	Ebert L, Meuter S, Moser B. Homing and function of human skin gammadelta T cells and NK cells: relevance for tumor surveillance. J Immunol. 2006;176:4331-6 pubmed
immunocytochemistry; human	Hewitt R, Lissina A, Green A, Slay E, Price D, Sewell A. The bisphosphonate acute phase response: rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statins. Clin Exp Immunol. 2005;139:101-11 pubmed
flow cytometry; human	Green A, Lissina A, Hutchinson S, Hewitt R, Temple B, James D, et al. Recognition of nonpeptide antigens by human V gamma 9V delta 2 T cells requires contact with cells of human origin. Clin Exp Immunol. 2004;136:472-82 pubmed
	Oberg H, Kellner C, Gonnermann D, Sebens S, Bauerschlag D, Gramatzki M, et al. Tribody [(HER2)2xCD16] Is More Effective Than Trastuzumab in Enhancing γδ T Cell and Natural Killer Cell Cytotoxicity Against HER2-Expressing Cancer Cells. Front Immunol. 2018;9:814 pubmed publisher
	Albertsson A, Zhang X, Vontell R, Bi D, Bronson R, Supramaniam V, et al. γδ T Cells Contribute to Injury in the Developing Brain. Am J Pathol. 2018;188:757-767 pubmed publisher
	Ali Z, Yan L, Plagman N, Reichenberg A, Hintz M, Jomaa H, et al. Gammadelta T cell immune manipulation during chronic phase of simian-human immunodeficiency virus infection [corrected] confers immunological benefits. J Immunol. 2009;183:5407-17 pubmed publisher
	Toulon A, Breton L, Taylor K, Tenenhaus M, Bhavsar D, Lanigan C, et al. A role for human skin-resident T cells in wound healing. J Exp Med. 2009;206:743-50 pubmed publisher
	Brandes M, Willimann K, Lang A, Nam K, Jin C, Brenner M, et al. Flexible migration program regulates gamma delta T-cell involvement in humoral immunity. Blood. 2003;102:3693-701 pubmed
	Zhou D, Lai X, Shen Y, Sehgal P, Shen L, Simon M, et al. Inhibition of adaptive Vgamma2Vdelta2+ T-cell responses during active mycobacterial coinfection of simian immunodeficiency virus SIVmac-infected monkeys. J Virol. 2003;77:2998-3006 pubmed
	Cipriani B, Borsellino G, Poccia F, Placido R, Tramonti D, Bach S, et al. Activation of C-C beta-chemokines in human peripheral blood gammadelta T cells by isopentenyl pyrophosphate and regulation by cytokines. Blood. 2000;95:39-47 pubmed
	Yeh C, Bulmer J, Hsi B, Tian W, Rittershaus C, Ip S. Monoclonal antibodies to T cell receptor gamma/delta complex react with human endometrial glandular epithelium. Placenta. 1990;11:253-61 pubmed

product information

Product Type :

Antibody

Product Name :

TCR V delta 1 Monoclonal Antibody (TS8.2)

Catalog # :

TCR1730

Quantity :

200 ug

Price :

US 502.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1-2 ug/test, Immunohistochemistry (Frozen): Assay-dependent, T-Cell Activation: Assay-dependent

Species :

Human

Clone :

TS8.2

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The T Cell Receptor gamma-delta (TCR gamma delta) is a heterodimeric membrane receptor that consists of the highly variable gamma and delta chains expressed as part of a complex with the invariant CD3 proteins. Gamma-delta T cells are less frequent than alpha-beta T cells but compose a substantial part of T cells found at epithelial borders including the gut mucosa resident intraepithelial lymphocytes (IEL). The antigenic stimuli required for gamma-delta T cell receptor activation are not well understood and are thought to be mainly MHC class-independent.

Immunogen :

Human TCR V delta 1

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1-2 ug/test, Immunohistochemistry (Frozen): Assay-dependent, T-Cell Activation: Assay-dependent

more info or order :

Invitrogen product webpage