Human PNAS4 (aa 7-96) Control Fragment Recombinant Protein | Invitrogen RP-99772 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human PNAS4 (aa 7-96) Control Fragment Recombinant Protein

catalog :

RP-99772

quantity :

100 uL

price :

US 259.00

product information

Product Type :

Protein

Product Name :

Human PNAS4 (aa 7-96) Control Fragment Recombinant Protein

Catalog # :

RP-99772

Quantity :

100 uL

Price :

US 259.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Species :

Human

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

PNAS4 is a highly conserved protein that shares high homology from plants to animals. It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4. PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS, SKOV3, and A549. PNAS4 inhibits tumor cell proliferation through the following mechanisms: (i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway. Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine. At least two isoforms of PNAS4 are known to exist.

Format :

Liquid

Applications w/Dilutions :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Aliases :

5830417C01Rik; C1orf121; cb238; CGI-146; DESI; DESI1; desi2; DeSI-2; desumoylating isopeptidase 1; desumoylating isopeptidase 2; Deubiquitinase DESI2; Fam152a; family with sequence similarity 152, member A; fi12d12; hypothetical protein LOC445138; pnas4; PNAS-4; PPPDE peptidase domain containing 1; PPPDE peptidase domain-containing protein 1; Pppde1; Protein FAM152A; sb:cb238; si:ch211-132e22.3; wu:fi12d12; zgc:100860