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protein

Human ENOSF1 (aa 366-436) Control Fragment Recombinant Protein

RP-98235

100 uL

US 259.00

Human ENOSF1 (aa 366-436) Control Fragment Recombinant Protein

RP-98235

100 uL

US 259.00

Recombinant

purified

Human

Blocking Assay: Assay-dependent, Control: Assay-dependent

Human

-20 C, Avoid Freeze/Thaw Cycles

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.

Liquid

Blocking Assay: Assay-dependent, Control: Assay-dependent

antisense RNA to thymidylate synthase; enolase superfamily member 1; ENOSF1; HSRTSBETA; L-fuconate dehydratase; mitochondrial enolase superfamily member 1; rTS; rTS alpha; rTS beta; TYMSAS