Human PIK3R6 (aa 636-741) Control Fragment Recombinant Protein | Invitrogen RP-93428 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human PIK3R6 (aa 636-741) Control Fragment Recombinant Protein

catalog :

RP-93428

quantity :

100 uL

price :

US 259.00

product information

Product Type :

Protein

Product Name :

Human PIK3R6 (aa 636-741) Control Fragment Recombinant Protein

Catalog # :

RP-93428

Quantity :

100 uL

Price :

US 259.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Species :

Human

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

p87PIKAP (p87 PI3K adapter protein), also known as PIK3R6 (phosphoinositide-3-kinase, regulatory subunit 6), p84 or HsT41028, is a 754 amino acid cytoplasmic protein that functions as a regulatory subunit of the PI 3-kinase p110 complex. Expressed in heart, dendritic cells, macrophages and neutrophils, p87PIKAP drives PI 3-kinase p110 activation, interacts with PDE3B and is thought to cause the two proteins to form a scaffolding interaction. The gene encoding p87PIKAP maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1, 200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

Format :

Liquid

Applications w/Dilutions :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Aliases :

BB220380; C17orf38; HsT41028; p84; p84 PI3K adapter protein; p84 PIKAP; p87 phosphoinositide 3-kinase gamma (PI3Kg) adapter protein; p87 phosphoinositide 3-kinase gamma adapter; p87 PI3K adapter protein; p87(PIKAP); p87PIKAP; Phosphoinositide 3-kinase gamma adapter protein of 87 kDa; Phosphoinositide 3-kinase regulatory subunit 6; phosphoinositide-3-kinase regulatory subunit 6; phosphoinositide-3-kinase, regulatory subunit 6; PI3Kgamma adapter protein of 87 kDa; PIK3R6; RGD1560850