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protein

Human SPINK6 Control Fragment Recombinant Protein

RP-90497

100 uL

US 259.00

Human SPINK6 Control Fragment Recombinant Protein

RP-90497

100 uL

US 259.00

Recombinant

purified

Human

Blocking Assay: Assay-dependent, Control: Assay-dependent

Human

-20 C, Avoid Freeze/Thaw Cycles

SPINK6 (serine peptidase inhibitor, Kazal type 6), also known as BUSI2, is an 80 amino acid secreted protein that contains one kazal-like domain and is thought to function as a serine protease inhibitor. The gene encoding SPINK6 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also associated with chromosome 5 and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute mye-logenous leukemias and myelodysplastic syndrome.

Liquid

Blocking Assay: Assay-dependent, Control: Assay-dependent

acrosin inhibitor; BUSI2; EG433180; Kallikrein inhibitor; Kazal type serine protease inhibitor 1; protease inhibitor H; serine peptidase inhibitor, Kazal type 6; serine protease inhibitor Kazal-type 6; Spink5l1; Spink6; UNQ844; UNQ844/PRO1782