This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human RTF1 (aa 392-516) Control Fragment Recombinant Protein
catalog :
RP-89460
quantity :
100 uL
price :
US 259.00
product information
Product Type :
Protein
Product Name :
Human RTF1 (aa 392-516) Control Fragment Recombinant Protein
Catalog # :
RP-89460
Quantity :
100 uL
Price :
US 259.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Human
Applications :
Blocking Assay: Assay-dependent, Control: Assay-dependent
Species :
Human
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Three isoforms of serine/threonine kinases, designated alphaPAK p68, betaPAK p65 and gammaPAK p62, have been shown to exhibit a high degree of sequence homology with the S. cerevisiae kinase Ste 20, involved in pheromone signaling. The alpha, beta and gammaPAK isoforms complex specifically with Rac1 and Cdc42 in their active GTP-bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation. There are eight sites of autophosphorylation on gammaPAK, including Ser 19, Ser 141 and Thr 402, and phosphorylation of Ser 141 and Thr 402 is correlated with gammaPAK activation. Once phosphorylated and their affinity for Rac/Cdc42 reduced, the PAK isoforms disassociate from the complex to seek downstream substrates.
Format :
Liquid
Applications w/Dilutions :
Blocking Assay: Assay-dependent, Control: Assay-dependent
Aliases :
2900005O08Rik; 6530416A09Rik; AI853581; AU043144; AW553985; cbp82; CG10955; CG10955-PA; CG10955-PB; Dmel CG10955; Dmel_CG10955; dRtf1; gene trap locus 7; Gtl7; KIAA0252; ortholog of mouse gene trap locus 7; RNA polymerase-associated protein Rtf1; RNA polymerase-associated protein RTF1 homolog; Rtf1; RTF1 homolog, Paf1/RNA polymerase II complex component; Rtf1 Paf1/RNA polymerase II complex component homolog; Rtf1, Paf1/RNA polymerase II complex component, homolog; Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae); Rtf1-PA; Rtf1-PB
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA