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protein

Human OPRK1 (aa 339-380) Control Fragment Recombinant Protein

RP-108531

100 uL

US 259.00

Human OPRK1 (aa 339-380) Control Fragment Recombinant Protein

RP-108531

100 uL

US 259.00

Recombinant

purified

Human

Blocking Assay: Assay-dependent, Control: Assay-dependent

Human

-20 C, Avoid Freeze/Thaw Cycles

This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Liquid

Blocking Assay: Assay-dependent, Control: Assay-dependent

kappa opioid receptor; kappa-type opioid receptor; KOPR1; KOR; K-OR-1; KOR-1; MSL-1; Opiate receptor, kappa-1; opioid receptor kappa 1; opioid receptor, kappa 1; opioid receptor, kappa 2; OPRK; OPRK1; Oprk2; Ork1; R21; Ror-d