Human LETMD1 (aa 161-224) Control Fragment Recombinant Protein | Invitrogen RP-107990 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human LETMD1 (aa 161-224) Control Fragment Recombinant Protein

catalog :

RP-107990

quantity :

100 uL

price :

US 259.00

product information

Product Type :

Protein

Product Name :

Human LETMD1 (aa 161-224) Control Fragment Recombinant Protein

Catalog # :

RP-107990

Quantity :

100 uL

Price :

US 259.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Species :

Human

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

HCCR-1 (human cervical cancer oncogene 1), also known as HCCR-2 or LETMD1, is a 360 amino acid single-pass membrane protein that is expressed in the kidney, liver, skeletal muscle, heart and brain. It is suggested that HCCR-1 may be involved in tumorigenesis and may function as a negative regulator of the p53 tumor suppressor. Overexpression of HCCR-1 may cause mitochondrial dysfunction that can lead to UVC or staurosporine-induced apoptosis resistance and progression of tumor formation. HCCR-1 is considered a candidate biomarker for breast cancer. Various human tumors including leukemia, lymphoma, and carcinomas of the breast, kidney, ovary, stomach, colon, and uterine cervix have high HCCR-1. Six isoforms exist due to alternative splicing events.

Format :

Liquid

Applications w/Dilutions :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Aliases :

1110019O13Rik; AI593524; BB130465; BB235638; Cervical cancer 1 proto-oncogene protein p40; cervical cancer proto-oncogene 2 protein; Cervical cancer receptor; HCCR1; HCCR-1; HCCR-2; HCRR-2; LETM1 domain containing 1; LETM1 domain-containing protein 1; LETMD1; MCC-32; Mccr; regulator of TP53; RGD1310591